Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL417277 | 0.82 | BACE1 (0.41) | BACE1SCN9ASCN7AKCNH2LOXL2 | |
| SCHEMBL1741598 | 0.76 | PTGS1 (0.38) | KCNH2KDM4ENPSR1 | |
| SCHEMBL10195034 | 0.71 | BACE1 (0.37) | BACE1SCN9ASCN7AKCNH2LOXL2 | |
| SCHEMBL406549 | 0.64 | MAPK1 (0.51) | SCN9ALMNANPSR1 | |
| SCHEMBL9105297 | 0.61 | LOXL2 (0.45) | BACE1SCN9ASCN7AKCNH2LOXL2 | |
| SCHEMBL413841 | 0.60 | MMP14 (0.42) | SCN9AKCNH2KDM4E | |
| SCHEMBL13064185 | 0.60 | GRM5 (0.50) | KDM4ELMNACYP1A2CYP2C19NPSR1 | |
| SCHEMBL31608506 | 0.60 | GRM5 (0.50) | KDM4ELMNACYP1A2CYP2C19NPSR1 | |
| SCHEMBL171631 | 0.59 | MEN1 (0.47) | BACE1SCN9ASCN7AKCNH2LOXL2 | |
| SCHEMBL30834433 | 0.59 | RXRA (0.35) | ALOX5APFEN1BACE1SCN9ASCN7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2387569-A1 | NOVEL HERBICIDES | Syngenta Limited (GB) | 2011-11-23 | — | — | EP | disclosed |
| WO-2010081755-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2010-07-22 | — | — | WO | disclosed |