SCHEMBL1742210

SCHEMBL1742210

CC(C)(C)OC(=O)N[C@H](CN)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CTSK P43235 7/20 0.50
CTSS P25774 6/20 0.50
PPARA Q07869 7/20 0.48
PPARG P37231 6/20 0.48
CTSL P07711 1/20 0.48
CTSB P07858 1/20 0.48
ACE P12821 1/20 0.47
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA7 P43166 1/20 0.46
PPARD Q03181 2/20 0.46
MEN1 O00255 1/20 0.45
GAA P10253 1/20 0.45
KMT2A Q03164 1/20 0.45
IDO1 P14902 1/20 0.44
ITGB3 P05106 1/20 0.44
ITGA2B P08514 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL646750 1.00 CTSK (0.50) CTSKCTSSPPARAPPARGCTSL
SCHEMBL206031 1.00 CTSK (0.50) CTSKCTSSPPARAPPARGCTSL
Hydrochloric Acid SCHEMBL16235893 0.98 CTSK (0.49) CTSKCTSSPPARAPPARGCTSL
Hydrochloric Acid SCHEMBL14471562 0.98 CTSK (0.49) CTSKCTSSPPARAPPARGCTSL
SCHEMBL303955 0.86 CTSK (0.49) CTSKCTSSPPARAPPARGCTSL
SCHEMBL303956 0.86 CTSK (0.49) CTSKCTSSPPARAPPARGCTSL
SCHEMBL2612149 0.86 CTSK (0.49) CTSKCTSSPPARAPPARGCTSL
SCHEMBL25256775 0.85 CYP1A2 (0.47) CTSKCTSSCTSLCTSBCA1
SCHEMBL20783244 0.85 CYP1A2 (0.47) CTSKCTSSCTSLCTSBCA1
SCHEMBL2393366 0.85 CYP1A2 (0.47) CTSKCTSSCTSLCTSBCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119751411-A Aggregation-induced emission probe design, synthesis and sterilization application based on bioorthogonal reaction metabolism anchoring living bacteria strategy 华南农业大学 2025-04-04 CN claimed
EP-3828163-B1 NOVEL P62 LIGAND COMPOUND, AND COMPOSITION FOR PREVENTING, ALLEVIATING, OR TREATING PROTEINOPATHIES COMPRISING SAME AUTOTAC INC (KR) 2026-05-20 EP disclosed
EP-4656638-A2 PYRAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF Japan Tobacco Inc. (JP) 2025-12-03 EP disclosed
WO-2025235389-A1 P53 MODULATORS NESTED THERAPEUTICS, INC. (US) 2025-11-13 WO disclosed
US-12427346-B2 P62 ligand compound, and composition for preventing, ameliorating or treating proteinopathies comprising the same AUTOTAC INC. (KR) 2025-09-30 US disclosed
WO-2025132943-A1 DECAHYDROQUINOLINES AS DNA POLYMERASE THETA INHIBITORS BREAKPOINT THERAPEUTICS GMBH (DE) 2025-06-26 WO disclosed
WO-2025108986-A1 2-AMINO-N-(OXO-ARYL-LAMBDA6-SULFANYLIDENE)ACETAMIDE COMPOUNDS AND THEIR THERAPEUTIC USE Oxford Drug Design Limited (GB) 2025-05-30 WO disclosed
CN-119751411-A Aggregation-induced emission probe design, synthesis and sterilization application based on bioorthogonal reaction metabolism anchoring living bacteria strategy 华南农业大学 2025-04-04 CN disclosed
US-12178842-B2 PCSK9 antagonist compounds MERCK SHARP & DOHME LLC (US) 2024-12-31 US disclosed
WO-2024215802-A1 BENZOFURANYL AND BENZOTHIENYL COMPOUNDS AS P53 MODULATORS NESTED THERAPEUTICS, INC. (US) 2024-10-17 WO disclosed
EP-0945445-B9 1,5-BENZODIAZEPINE DERIVATIVES ZERIA PHARM CO LTD (JP) 2005-12-28 EP disclosed
US-20040225006-A1 (Hetero) bicyclymethanesulfonylamino-substituted hydroxamic acid derivates SMITHKLINE BEECHAM P.L.C. 2004-11-11 US disclosed
US-20030199571-A1 (Hetero) Bicyclymethanesulfonylamino-substituted hydroxamic acid derivatives SMITHKLINE BEECHAM P.L.C. (GB) 2003-10-23 US disclosed
EP-0945445-B1 1,5-BENZODIAZEPINE DERIVATIVES ZERIA PHARM CO LTD (JP) 2003-09-03 EP disclosed
EP-1244616-A1 (HETERO)BICYCLYLMETHANESULFONYLAMINO-SUBSTITUTED HYDROXAMIC ACID DERIVATIVES SmithKline Beecham plc (GB) 2002-10-02 EP disclosed
US-6344452-B1 GASTRIN RECEPTOR ANTAGONIST, GASTROINTESTINAL DISORDERS, ETC ZERIA PHARMACEUTICALS CO., LTD. (JP) 2002-02-05 US disclosed
WO-2001047874-A1 (HETERO)BICYCLYMETHANESULFONYLAMINO-SUBSTITUTED HYDROXAMIC ACID DERIVATIVES SMITHKLINE BEECHAM P.L.C. (GB) 2001-07-05 WO disclosed
US-6239131-B1 WHICH HAVE GASTRIN AND/OR CCK-B (CHOLECYSTOKININ-B) RECEPTOR ANTAGONISM, USEFUL AS REMEDIES FOR GASTRIC ULCER AND GASTROINTESTINAL MOVEMENT DISORDER. ZERIA PHARMACEUTICAL CO., LTD. (JP) 2001-05-29 US disclosed
EP-1085014-A1 1,5-BENZODIAZEPINE DERIVATIVES Zeria Pharmaceutical Co., Ltd. (JP) 2001-03-21 EP disclosed
EP-0945445-A1 1,5-BENZODIAZEPINE DERIVATIVES ZERIA PHARMACEUTICAL CO., LTD. (JP) 1999-09-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12427346-B2 P62 ligand compound, and composition for preventing, ameliorating or treating proteinopathies comprising the same SQSTM1, ATG7, BECN1 CTSK 1671/4885CTSS 908/4885PPARA 385/4885
US-12178842-B2 PCSK9 antagonist compounds PCSK9, PCSK7, PCSK6 CTSK 193/4885CTSS 287/4885PPARA 1100/4885
US-20030199571-A1 (Hetero) Bicyclymethanesulfonylamino-substituted hydroxamic acid derivatives CD40, CD22, CD2 CTSK 1217/4885CTSS 561/4885PPARA 3785/4885
US-20040225006-A1 (Hetero) bicyclymethanesulfonylamino-substituted hydroxamic acid derivates CD40, TNFRSF1A, CD2 CTSK 1531/4885CTSS 764/4885PPARA 3859/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.