Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 16/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | UBE2N | P61088 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18690941 | 0.92 | HTR6 (0.48) | HTR6KDM4EUBE2NHTR2CHTR2A | |
| SCHEMBL17422096 | 0.90 | HTR6 (0.52) | HTR6KDM4EUBE2NHTR2CHTR2A | |
| SCHEMBL2229621 | 0.89 | KDM4E (0.53) | HTR6KDM4EUBE2NHTR2CHTR1D | |
| SCHEMBL17422025 | 0.86 | HTR6 (0.52) | HTR6HTR2CDRD3HTR2A | |
| SCHEMBL17422051 | 0.86 | HTR6 (0.56) | HTR6 | |
| SCHEMBL2230089 | 0.86 | KDM4E (0.48) | HTR6KDM4EUBE2NHTR2CHTR1D | |
| SCHEMBL17422123 | 0.85 | HTR6 (0.54) | HTR6HTR2C | |
| SCHEMBL18690903 | 0.84 | HTR6 (0.72) | HTR6HTR2C | |
| SCHEMBL31298699 | 0.84 | KDM4E (0.59) | HTR6KDM4EUBE2NHTR2CHTR1D | |
| SCHEMBL17422129 | 0.83 | HTR6 (0.52) | HTR6HTR2CDRD3HTR2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3166924-B1 | AROMATIC HETEROCYCLIC DERIVATIVES AND PHARMACEUTICAL APPLICATIONS THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2019-02-20 | — | — | EP | disclosed |
| US-9974785-B2 | Aromatic heterocyclic derivatives and pharmaceutical applications thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2018-05-22 | — | — | US | disclosed |
| EP-3166924-A1 | AROMATIC HETEROCYCLIC DERIVATIVES AND PHARMACEUTICAL APPLICATIONS THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2017-05-17 | — | — | EP | disclosed |
| US-20170096392-A1 | AROMATIC HETEROCYCLIC DERIVATIVES AND PHARMACEUTICAL APPLICATIONS THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2017-04-06 | — | — | US | disclosed |
| WO-2016004882-A1 | AROMATIC HETEROCYCLIC DERIVATIVES AND PHARMACEUTICAL APPLICATIONS THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-01-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170096392-A1 | AROMATIC HETEROCYCLIC DERIVATIVES AND PHARMACEUTICAL APPLICATIONS THEREOF | HTR6, HTR3A, HTR5A | HTR6 1/4885KDM4E 3544/4885UBE2N 2993/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.