Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 10/20 | 0.50 |
| ▸ | NOD2 | Q9HC29 | 3/20 | 0.49 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.46 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4304442 | 0.90 | HTR6 (0.54) | HTR6PKM | |
| Hydrochloric Acid SCHEMBL4316251 | 0.89 | HTR6 (0.53) | HTR6PKM | |
| Hydrochloric Acid SCHEMBL6521806 | 0.89 | HTR6 (0.53) | HTR6PKM | |
| SCHEMBL4309788 | 0.88 | PKM (0.45) | ALOX5HTR6PKMHTTLMNA | |
| SCHEMBL4316005 | 0.88 | MAPT (0.51) | HTR6NOD2NOD1ALDH1A1ALDH3A1 | |
| Hydrochloric Acid SCHEMBL6518351 | 0.87 | HTR6 (0.50) | HTR6NOD2NOD1ALDH1A1ALDH3A1 | |
| Hydrochloric Acid SCHEMBL6518308 | 0.87 | HTR6 (0.44) | ALOX5HTR6PKMHTTLMNA | |
| SCHEMBL4317729 | 0.86 | HTR6 (0.45) | HTR6GAAPKM | |
| SCHEMBL4315943 | 0.85 | LTA4H (0.48) | HTR6SMN1; SMN2ALDH1A1PKMLMNA | |
| Hydrochloric Acid SCHEMBL6519613 | 0.85 | HTR6 (0.44) | HTR6GAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3166924-A1 | AROMATIC HETEROCYCLIC DERIVATIVES AND PHARMACEUTICAL APPLICATIONS THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2017-05-17 | — | — | EP | disclosed |
| WO-2016004882-A1 | AROMATIC HETEROCYCLIC DERIVATIVES AND PHARMACEUTICAL APPLICATIONS THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-01-14 | — | — | WO | disclosed |