Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CASP7 | P55210 | 2/20 | 0.40 |
| ▸ | TDP2 | O95551 | 1/20 | 0.40 |
| ▸ | CASP9 | P55211 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13281083 | 0.77 | HSD17B10 (0.48) | HSD17B10TDP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL30937695 | 0.77 | HSD17B10 (0.44) | HSD17B10TDP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL9125629 | 0.74 | HSD17B10 (0.41) | HSD17B10TDP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL9125609 | 0.74 | ALDH1A1 (0.43) | HSD17B10TDP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL30937544 | 0.73 | AKR1C1 (0.46) | HSD17B10TDP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL5369495 | 0.73 | AKR1C1 (0.46) | HSD17B10TDP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL632435 | 0.73 | LMNA (0.43) | HSD17B10TDP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL5368690 | 0.72 | AKR1C1 (0.49) | TDP1ALDH1A1KMT2AMEN1GPR35 | |
| SCHEMBL5366796 | 0.72 | ALDH1A1 (0.41) | HSD17B10TDP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL22566 | 0.71 | HSD17B10 (0.67) | HSD17B10TDP1ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102291989-B | Herbicide derived from cyclopentanedione | 辛根塔有限公司 | 2016-08-03 | — | — | CN | disclosed |
| EP-2389066-A1 | CYCLOPENTADIONE DERIVED HERBICIDES | Syngenta Limited (GB) | 2011-11-30 | — | — | EP | disclosed |
| WO-2010102848-A1 | CYCLOPENTADIONE DERIVED HERBICIDES | SYNGENTA LIMITED (GB) | 2010-09-16 | — | — | WO | disclosed |