Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | CASP9 | P55211 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13281083 | 0.74 | HSD17B10 (0.48) | HSD17B10TDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL30937695 | 0.74 | HSD17B10 (0.44) | HSD17B10TDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL29415666 | 0.73 | KMT2A (0.36) | TDP1ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL19207560 | 0.73 | KMT2A (0.36) | TDP1ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL9125609 | 0.71 | ALDH1A1 (0.43) | HSD17B10TDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL5739965 | 0.70 | CASP7 (0.35) | HSD17B10TDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL30937544 | 0.70 | AKR1C1 (0.46) | HSD17B10TDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL5369495 | 0.70 | AKR1C1 (0.46) | HSD17B10TDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL8830302 | 0.69 | ALOX15 (0.36) | ALDH1A1CASP7TSHRL3MBTL1SMN1; SMN2 | |
| SCHEMBL19040317 | 0.69 | ALDH1A1 (0.48) | HSD17B10TDP1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5453545-A | Herbicide intermediate o-nitrophenyl cyclopropyl ketone and a method for the preparation thereof | AMERICAN CYANAMID CO. (US) | 1995-09-26 | — | — | US | disclosed |
| US-5364968-A | Herbicide intermediate o-nitrophenyl cyclopropyl ketone and a method for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1994-11-15 | — | — | US | disclosed |