Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | HPRT1 | P00492 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2643488 | 0.78 | ALDH1A1 (0.39) | LMNACYP3A4MAPTMAPK1APEX1 | |
| SCHEMBL29639994 | 0.78 | ALDH1A1 (0.39) | LMNACYP3A4MAPTMAPK1APEX1 | |
| SCHEMBL17422017 | 0.76 | CYP3A4 (0.36) | LMNACYP3A4MAPTHPRT1NPC1 | |
| SCHEMBL1644904 | 0.74 | LMNA (0.48) | LMNACYP3A4MAPTPMP22SMN1; SMN2 | |
| SCHEMBL18902560 | 0.70 | PARP1 (0.30) | — | |
| SCHEMBL17231596 | 0.69 | NPC1 (0.32) | MAPTNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL23954295 | 0.69 | ABL1 (0.34) | LMNAMAPTMAPK1NPC1RAB9A | |
| SCHEMBL30956235 | 0.68 | HPRT1 (0.61) | LMNACYP3A4MAPTMAPK1APEX1 | |
| SCHEMBL8895152 | 0.68 | PIM1 (0.34) | ALDH1A1 | |
| SCHEMBL28462174 | 0.66 | HSD17B10 (0.37) | LMNAMAPTHPRT1PAX8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016005992-A1 | SUBSTITUTED NAPHTHO[2,1-b][1,10]PHENANTHROLINE BASED FLUORESCENT DYES AND APPLICATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-01-14 | — | — | WO | disclosed |