SCHEMBL8895152

SCHEMBL8895152

C1=Cc2c(c3c4ccccc4cnc3c3ccccc23)NC1

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 4/20 0.34
PIM3 Q86V86 1/20 0.34
KDM4E B2RXH2 1/20 0.33
GPR3 P46089 1/20 0.33
ALDH1A1 P00352 1/20 0.32
CDK4 P11802 1/20 0.31
CCND1 P24385 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14310463 0.75
SCHEMBL16535869 0.69 KDM4E (0.48) PIM1PIM3KDM4EGPR3ALDH1A1
SCHEMBL6919575 0.69 ALDH1A1 (0.49) PIM1PIM3KDM4EGPR3ALDH1A1
SCHEMBL21791031 0.68 MAOA (0.31) KDM4EALDH1A1
SCHEMBL17422686 0.68 LMNA (0.37) ALDH1A1
SCHEMBL22049815 0.67 KDM4E (0.45) PIM1PIM3KDM4EGPR3ALDH1A1
SCHEMBL7893958 0.66 KDM4E (0.41) PIM1PIM3KDM4EGPR3ALDH1A1
SCHEMBL7901264 0.64 KDM4E (0.39) PIM1PIM3KDM4EGPR3ALDH1A1
SCHEMBL7900644 0.64 KDM4E (0.39) PIM1PIM3KDM4EGPR3ALDH1A1
SCHEMBL19748987 0.63 KDM4E (0.60) PIM1PIM3KDM4EGPR3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0564224-B1 Organic electroluminescene device PIONEER ELECTRONIC CORP (JP) 1997-05-28 EP disclosed
US-5393614-A Organic electroluminescence device PIONEER ELECTRONIC CORPORATION (JP) 1995-02-28 US disclosed
EP-0564224-A2 Organic electroluminescene device PIONEER ELECTRONIC CORPORATION (JP) 1993-10-06 EP disclosed