Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | AGXT | P21549 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13538390 | 0.82 | SIGMAR1 (0.52) | TAAR1MEN1KMT2ASIGMAR1MAOB | |
| SCHEMBL13220639 | 0.82 | TAAR1 (0.57) | TAAR1MEN1KMT2ASIGMAR1IDO1 | |
| SCHEMBL19524579 | 0.81 | SIGMAR1 (0.51) | TAAR1MEN1KMT2ASIGMAR1MAOB | |
| SCHEMBL21726124 | 0.80 | PARP1 (0.42) | IDO1PARP1 | |
| SCHEMBL15721667 | 0.80 | PARP1 (0.42) | IDO1PARP1 | |
| SCHEMBL27407790 | 0.80 | RIPK1 (0.48) | TAAR1MEN1KMT2AIDO1PARP1 | |
| SCHEMBL26874493 | 0.79 | PARP1 (0.41) | IDO1PARP1 | |
| SCHEMBL15427659 | 0.79 | TRPA1 (0.44) | IDO1PARP1 | |
| SCHEMBL8208663 | 0.77 | TAAR1 (0.52) | TAAR1MEN1KMT2AIDO1 | |
| SCHEMBL2758515 | 0.76 | HDAC4 (0.53) | MEN1KMT2AIDO1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385940-A1 | 2,4,6-TRI-(HETEROARYLPHENYL)-PYRIDINES AND ELECTRON-TRANSPORTING MATERIALS COMPRISING THEM | General Electric Company (US) | 2011-11-16 | — | — | EP | disclosed |
| US-8041982-B2 | Real time clock | TEXAS INSTRUMENTS INCORPORATED (US) | 2011-10-18 | — | — | US | disclosed |
| WO-2010080471-A1 | 2,4,6-TRI-(HETEROARYLPHENYL)-PYRIDINES AND ELECTRON-TRANSPORTING MATERIALS COMPRISING THEM | GENERAL ELECTRIC COMPANY (US) | 2010-07-15 | — | — | WO | disclosed |