Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 4/20 | 0.54 |
| ▸ | PTPN7 | P35236 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SELP | P16109 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17521392 | 0.82 | HMGCR (0.33) | HMGCRPTPN7LMNAMAPTMAPK1 | |
| SCHEMBL21134751 | 0.81 | LMNA (0.50) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL10398060 | 0.79 | HMGCR (0.61) | HMGCRPTPN7LMNAMAPTMAPK1 | |
| SCHEMBL10024786 | 0.79 | HMGCR (0.57) | HMGCRPTPN7LMNAMAPTMAPK1 | |
| SCHEMBL22007563 | 0.79 | LMNA (0.45) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL17422869 | 0.78 | HMGCR (0.55) | HMGCRPTPN7LMNAMAPTSELP | |
| SCHEMBL8008522 | 0.78 | HMGCR (0.68) | HMGCRPTPN7LMNASELP | |
| SCHEMBL15287851 | 0.78 | HMGCR (0.51) | HMGCRPTPN7LMNAMAPTMAPK1 | |
| SCHEMBL22006641 | 0.78 | LMNA (0.42) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL5054228 | 0.77 | ALDH1A1 (0.77) | HMGCRLMNAALDH1A1PRKCAPRKCE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10101277-B2 | Poly(methyl methacrylate)-supported polydiacetylene films as colorimetric and/or fluorescent detectors | B.G. NEGEV TECHNOLOGIES & APPLICATIONS LTD. AT BEN-GURION UNIVERSITY (IL) | 2018-10-16 | — | — | US | claimed |
| US-20160041102-A1 | POLY(METHYL METHACRYLATE)-SUPPORTED POLYDIACETYLENE FILMS AS COLORIMETRIC AND/OR FLUORESCENT DETECTORS | B.G. NEGEV TECHNOLOGIES & APPLICATIONS LTD. AT BEN-GURION UNIVERSITY (IL) | 2016-02-11 | — | — | US | claimed |
| US-10101277-B2 | Poly(methyl methacrylate)-supported polydiacetylene films as colorimetric and/or fluorescent detectors | B.G. NEGEV TECHNOLOGIES & APPLICATIONS LTD. AT BEN-GURION UNIVERSITY (IL) | 2018-10-16 | — | — | US | disclosed |
| US-20160041102-A1 | POLY(METHYL METHACRYLATE)-SUPPORTED POLYDIACETYLENE FILMS AS COLORIMETRIC AND/OR FLUORESCENT DETECTORS | B.G. NEGEV TECHNOLOGIES & APPLICATIONS LTD. AT BEN-GURION UNIVERSITY (IL) | 2016-02-11 | — | — | US | disclosed |
| WO-2016005987-A1 | POLY (METHYL METHACRYLATE)-SUPPORTED POLYDIACETYLENE FILMS AS COLORIMETRIC AND/OR FLUORESCENT DETECTORS | B.G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD., AT BEN-GURION UNIVERSITY (IL) | 2016-01-14 | — | — | WO | disclosed |