SCHEMBL17423219

SCHEMBL17423219

Clc1ccc2cc3ccccc3nc2c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.65
ALDH1A1 P00352 4/20 0.65
HPGD P15428 3/20 0.65
GLA P06280 3/20 0.65
ACHE P22303 2/20 0.65
HTR3A P46098 1/20 0.59
CYP2A6 P11509 1/20 0.54
NR4A2 P43354 1/20 0.53
KMT2A Q03164 3/20 0.46
ESR1 P03372 1/20 0.45
ESR2 Q92731 1/20 0.45
NQO2 P16083 1/20 0.44
CNR2 P34972 1/20 0.43
LMNA P02545 3/20 0.42
KDM4E B2RXH2 3/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
POLB P06746 1/20 0.42
GAA P10253 1/20 0.42
PTBP1 P26599 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7608692 0.89 NR4A2 (0.52) MAPTALDH1A1HPGDGLAACHE
SCHEMBL7905050 0.87 MAPT (0.65) MAPTALDH1A1HPGDGLAACHE
Acridine SCHEMBL4972293 0.81 ALDH1A1 (1.00) MAPTALDH1A1HPGDGLAACHE
Acridine SCHEMBL8339 0.81 ALDH1A1 (1.00) MAPTALDH1A1HPGDGLAACHE
Acridine SCHEMBL3045498 0.81 ALDH1A1 (1.00) MAPTALDH1A1HPGDGLAACHE
Acridine SCHEMBL29352289 0.81 ALDH1A1 (1.00) MAPTALDH1A1HPGDGLAACHE
Acridine SCHEMBL1772714 0.81 ALDH1A1 (1.00) MAPTALDH1A1HPGDGLAACHE
SCHEMBL29856205 0.79 NQO2 (0.56) MAPTALDH1A1HPGDGLAACHE
SCHEMBL5157721 0.79 NQO2 (0.56) MAPTALDH1A1HPGDGLAACHE
SCHEMBL13156489 0.79 MAPT (0.83) MAPTALDH1A1HPGDGLAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107973749-A Nitrogen anthracene compound and its synthetic method and application 华东师范大学 2018-05-01 CN claimed
CN-107973749-A Nitrogen anthracene compound and its synthetic method and application 华东师范大学 2018-05-01 CN disclosed
CN-107353212-A A kind of luminous organic material and its organic luminescent device 长春海谱润斯科技有限公司 2017-11-17 CN disclosed
WO-2016005979-A1 METHODS AND COMPOSITIONS FOR TREATING VIRAL INFECTIONS IN HONEYBEES THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI CENTER) (IL) 2016-01-14 WO disclosed
CN-103554023-B The synthetic method of acridine derivatives and the polycyclic acridine derivative of synthesis JILIN UNIVERSITY (CN) 2015-09-30 CN disclosed
CN-103554023-A Synthesis method of acridine derivative and synthesized polycyclic acridine derivative UNIV JILIN 2014-02-05 CN disclosed