Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17423219 | 0.89 | MAPT (0.65) | NR4A2ACHELMNAMEN1F2 | |
| SCHEMBL11057520 | 0.87 | LMNA (0.75) | NR4A2ACHELMNAMEN1F2 | |
| SCHEMBL12068392 | 0.82 | ALDH1A1 (0.57) | LMNAMEN1KMT2APDGFRBPDGFRA | |
| SCHEMBL16500490 | 0.82 | ESR1 (0.49) | NR4A2MEN1KMT2ADYRK1AF7 | |
| SCHEMBL12068383 | 0.80 | KDM4E (0.50) | PDGFRBPDGFRARXFP1MAPTALDH1A1 | |
| SCHEMBL5157381 | 0.80 | PIK3CG (0.58) | NR4A2LMNAMEN1KMT2ADYRK1A | |
| SCHEMBL30506415 | 0.79 | NR4A2 (0.54) | NR4A2LMNAHRH3PDGFRBPDGFRA | |
| SCHEMBL2133059 | 0.79 | NR4A2 (0.54) | NR4A2LMNAHRH3PDGFRBPDGFRA | |
| SCHEMBL28208080 | 0.79 | NR4A2 (0.44) | NR4A2LMNAKMT2AHRH3PDGFRB | |
| SCHEMBL278565 | 0.78 | NCF1 (0.56) | LMNAMEN1KMT2ACYP2A6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020051751-A1 | Pharmaceuticals and apparatus providing diagnosis and selective tissue necrosis | MILLS RANDELL L (US) | 2002-05-02 | — | — | US | disclosed |
| US-6224848-B1 | Pharmaceuticals providing diagnosis and selective tissue necrosis using Mossbauer absorber atom | MILLS RANDELL L (US) | 2001-05-01 | — | — | US | disclosed |
| EP-0316440-B1 | System and method for providing localized Mössbauer absorption in an organic medium | MILLS RANDELL L (US) | 1996-01-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020051751-A1 | Pharmaceuticals and apparatus providing diagnosis and selective tissue necrosis | TK2, POLB, ATP5PB | NR4A2 1088/4885ACHE 1301/4885LMNA 1311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.