Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | GSK3A | P49840 | 2/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 2/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | SCN4A | P35499 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25226425 | 0.69 | CCR8 (0.42) | GSK3AGSK3BDYRK1AALDH1A1BTK | |
| SCHEMBL16432224 | 0.69 | ERBB2 (0.46) | ERBB2DYRK1ALTA4HNPC1SCN4A | |
| SCHEMBL3530057 | 0.68 | NR4A2 (0.48) | BRD4ERBB2GSTP1LTA4HNPC1 | |
| SCHEMBL22710397 | 0.67 | ERBB2 (0.48) | ERBB2GSTP1LTA4HNPC1SCN4A | |
| SCHEMBL18741409 | 0.67 | PDE3B (0.43) | ERBB2GSTP1LTA4HNPC1SCN4A | |
| SCHEMBL24728843 | 0.67 | CHEK1 (0.44) | GSK3BDYRK1APRMT5WDR77KDM4E | |
| SCHEMBL30719652 | 0.66 | ATM (0.67) | ATMNPSR1GSK3AGSK3BDYRK1A | |
| SCHEMBL13923950 | 0.66 | KDR (0.59) | DYRK1ANPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL710318 | 0.66 | ATM (0.67) | ATMNPSR1GSK3AGSK3BDYRK1A | |
| SCHEMBL13946607 | 0.66 | XDH (0.45) | ERBB2GSTP1LTA4HNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3166608-A1 | AMINOPYRIDAZINONE COMPOUNDS AS PROTEIN KINASE INHIBITORS | Eternity Bioscience Inc. (US) | 2017-05-17 | — | — | EP | disclosed |
| WO-2016007185-A1 | AMINOPYRIDAZINONE COMPOUNDS AS PROTEIN KINASE INHIBITORS | Eternity Bioscience Inc. (US) | 2016-01-14 | — | — | WO | disclosed |