SCHEMBL17423892

SCHEMBL17423892

NCC(N)(c1ccccc1O)c1ccccc1O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.48
TSHR P16473 4/20 0.48
TDP1 Q9NUW8 2/20 0.48
TAAR1 Q96RJ0 3/20 0.40
KDM4E B2RXH2 3/20 0.39
MAPT P10636 3/20 0.39
HPGD P15428 3/20 0.39
ALOX15 P16050 2/20 0.39
HIF1A Q16665 2/20 0.39
HSD17B10 Q99714 2/20 0.39
NPC1 O15118 1/20 0.39
CA12 O43570 1/20 0.39
GMNN O75496 1/20 0.39
EGFR P00533 1/20 0.39
CA2 P00918 1/20 0.39
LMNA P02545 1/20 0.39
FYN P06241 1/20 0.39
POLB P06746 1/20 0.39
CA3 P07451 1/20 0.39
CYP3A4 P08684 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL1643176 0.89 ALDH1A1 (0.44) ALDH1A1TSHRTDP1TAAR1KDM4E
SCHEMBL5691722 0.79 ALDH1A1 (0.50) ALDH1A1TSHRTDP1TAAR1KDM4E
SCHEMBL5691713 0.77 IDO1 (0.48) ALDH1A1TSHRTDP1TAAR1KDM4E
SCHEMBL28501608 0.77 ALDH1A1 (0.72) ALDH1A1TSHRTDP1TAAR1KDM4E
SCHEMBL144360 0.76 ALDH1A1 (0.58) ALDH1A1TSHRTDP1TAAR1KDM4E
SCHEMBL8089067 0.75 ALDH1A1 (0.56) ALDH1A1TSHRTDP1TAAR1KDM4E
SCHEMBL11139625 0.75 ALDH1A1 (0.47) ALDH1A1TSHRTDP1TAAR1MAPT
SCHEMBL4601477 0.74 TAAR1 (0.41) ALDH1A1TSHRTDP1TAAR1MAPT
SCHEMBL6522563 0.73 ALDH1A1 (0.54) ALDH1A1TSHRTDP1TAAR1KDM4E
SCHEMBL650917 0.72 TSHR (0.48) ALDH1A1TSHRTDP1TAAR1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110923680-B Substituted electroless gold plating solution containing purine or pyrimidine compound having carbonyl oxygen and method using same MK化学科技有限公司 2021-09-24 CN disclosed
EP-3863612-A1 PROCESSES FOR PREPARING FUNCTIONALIZED CYCLOOCTENES Tambo, Inc. (US) 2021-08-18 EP disclosed
US-20180347038-A1 Elimination of H2S in Immersion Tin Plating Solution CITIBANK, N.A. 2018-12-06 US disclosed
EP-3319941-A1 A TWO-STEP PROCESS FOR PREPARING 3-SUBSTITUTED PHENYLALKYLAMINES SpecGx, LLC (US) 2018-05-16 EP disclosed
EP-3166923-A1 PROCESS FOR PREPARING SUBSTITUTED PHENYLALKANES Mallinckrodt LLC (US) 2017-05-17 EP disclosed
WO-2017011231-A1 A TWO-STEP PROCESS FOR PREPARING 3-SUBSTITUTED PHENYLALKYLAMINES MALLINCKRODT LLC (US) 2017-01-19 WO disclosed
WO-2016112243-A1 UREA DERIVATIVES OF AMPHOTERICIN B DERIVED FROM SECONDARY AMINES THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2016-07-14 WO disclosed
WO-2016040779-A1 UREA DERIVATIVES OF POLYENE MACROLIDE ANTIBIOTICS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2016-03-17 WO disclosed
WO-2016007823-A1 PROCESS FOR PREPARING SUBSTITUTED PHENYLALKANES MALLINCKRODT LLC (US) 2016-01-14 WO disclosed