Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KISS1R | Q969F8 | 4/20 | 0.57 |
| ▸ | FURIN | P09958 | 1/20 | 0.53 |
| ▸ | GNPAT | O15228 | 1/20 | 0.51 |
| ▸ | NPY4R | P50391 | 8/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.49 |
| ▸ | NPY1R | P25929 | 6/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.48 |
| ▸ | NPY2R | P49146 | 3/20 | 0.47 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.47 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | FCER2 | P06734 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17424377 | 0.90 | KISS1R (0.57) | KISS1RFURINGNPATNPY4RNPY5R | |
| SCHEMBL12035324 | 0.90 | NPY4R (0.60) | KISS1RFURINGNPATNPY4RNPY5R | |
| SCHEMBL17424417 | 0.88 | CA1 (0.46) | KISS1RFURINGNPATNPY4RNPY5R | |
| SCHEMBL17424416 | 0.84 | SIRT1 (0.45) | KISS1RFURINGNPAT | |
| SCHEMBL17424438 | 0.84 | NPY1R (0.42) | KISS1RFURINGNPATNPY4RNPY5R | |
| SCHEMBL17424374 | 0.84 | SIRT5 (0.46) | KISS1RFURINNPY4RNPY5RNPY1R | |
| SCHEMBL30045851 | 0.83 | KISS1R (0.61) | KISS1RGNPATNPY4RNPY5RNPY1R | |
| SCHEMBL17424392 | 0.82 | SIRT5 (0.47) | KISS1RFURINNPY4RNPY5RNPY1R | |
| SCHEMBL17424369 | 0.82 | SIRT5 (0.44) | KISS1RFURINNPY4RNPY5RNPY1R | |
| SCHEMBL12792618 | 0.82 | KISS1R (0.62) | KISS1RGNPATNPY4RNPY5RNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9233086-B2 | Inhibition of WDR5 interaction with its binding partners | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2016-01-12 | — | — | US | disclosed |