Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 6/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17424814 | 0.84 | THRB (0.46) | TSHRALDH1A1THRB | |
| SCHEMBL23095595 | 0.82 | TSHR (0.47) | TSHRALDH1A1CYP3A4POLBAPEX1 | |
| SCHEMBL27588151 | 0.80 | TSHR (0.59) | TSHRALDH1A1NAAARAD52NPSR1 | |
| SCHEMBL3951015 | 0.79 | ALDH1A1 (0.45) | TSHRALDH1A1HTTNPSR1LMNA | |
| SCHEMBL23095593 | 0.78 | THRB (0.41) | TSHRALDH1A1CYP3A4THRB | |
| SCHEMBL1175051 | 0.76 | TSHR (0.49) | TSHRALDH1A1TDP1NAAARAD52 | |
| SCHEMBL9646938 | 0.74 | TSHR (0.55) | TSHRALDH1A1CYP3A4POLBAPEX1 | |
| SCHEMBL8080880 | 0.73 | APP (0.34) | TSHR | |
| SCHEMBL11803516 | 0.72 | TSHR (0.69) | TSHRALDH1A1NAAARAD52NPSR1 | |
| SCHEMBL3503962 | 0.72 | TSHR (0.69) | TSHRALDH1A1NAAARAD52NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170172855-A1 | Compositions With Controlled Network Structure | TECHNISCHE UNIVERSITÄT WIEN (AT) | 2017-06-22 | — | — | US | disclosed |
| US-20170172855-A1 | Compositions With Controlled Network Structure | TECHNISCHE UNIVERSITÄT WIEN (AT) | 2017-06-22 | — | — | US | disclosed |
| US-20170156993-A1 | DENTAL MATERIALS WITH DEBONDING-ON-DEMAND PROPERTIES | TECHNISCHE UNIVERSITÄT WIEN (AT) | 2017-06-08 | — | — | US | disclosed |
| US-20170156993-A1 | DENTAL MATERIALS WITH DEBONDING-ON-DEMAND PROPERTIES | TECHNISCHE UNIVERSITÄT WIEN (AT) | 2017-06-08 | — | — | US | disclosed |
| WO-2016005540-A1 | DENTAL MATERIALS HAVING DEBONDING-ON-DEMAND PROPERTIES | IVOCLAR VIVADENT AG (LI) | 2016-01-14 | — | — | WO | disclosed |
| WO-2016005534-A1 | COMPOSITES HAVING A CONTROLLED NETWORK STRUCTURE | IVOCLAR VIVADENT AG (LI) | 2016-01-14 | — | — | WO | disclosed |
| EP-2965741-A1 | Composites with controlled network structure | Ivoclar Vivadent AG (LI) | 2016-01-13 | — | — | EP | disclosed |
| EP-2965740-A1 | Dental materials with debonding on demand properties | Ivoclar Vivadent AG (LI) | 2016-01-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170172855-A1 | Compositions With Controlled Network Structure | NCLN, RAD51, SMCHD1 | TSHR 4627/4885ALDH1A1 2901/4885CYP3A4 2866/4885 |
| US-20170156993-A1 | DENTAL MATERIALS WITH DEBONDING-ON-DEMAND PROPERTIES | DCLRE1A, RAD51, TERB1 | TSHR 3799/4885ALDH1A1 992/4885CYP3A4 2406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.