SCHEMBL17425489

SCHEMBL17425489

CC1(C)c2ccccc2-c2ccc(-c3nc(-c4ccc(-c5cccc6c5sc5c(-c7ccccc7)cccc56)cc4)nc(-c4ccc5c(c4)C(C)(C)c4ccccc4-5)n3)cc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIMK1 P53667 1/20 0.38
MEN1 O00255 4/20 0.35
KMT2A Q03164 4/20 0.35
ALDH1A1 P00352 3/20 0.35
MAPT P10636 3/20 0.35
HPGD P15428 3/20 0.35
ALOX5 P09917 1/20 0.34
KDM4E B2RXH2 2/20 0.34
LMNA P02545 1/20 0.34
GLA P06280 1/20 0.34
PDK2 Q15119 6/20 0.33
ACACA Q13085 2/20 0.33
ADORA2A P29274 1/20 0.33
ADORA1 P30542 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
NTSR1 P30989 1/20 0.32
MAPK1 P28482 2/20 0.32
HSD17B10 Q99714 2/20 0.32
USP2 O75604 2/20 0.32
CYP1A2 P05177 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17425487 0.98 LIMK1 (0.37) LIMK1MEN1KMT2AALDH1A1MAPT
SCHEMBL30103502 0.98 LIMK1 (0.37) LIMK1MEN1KMT2AALDH1A1MAPT
SCHEMBL17425526 0.98 LIMK1 (0.37) LIMK1MEN1KMT2AALDH1A1MAPT
SCHEMBL17640357 0.98 LIMK1 (0.38) LIMK1MEN1KMT2AALDH1A1MAPT
SCHEMBL17425673 0.97 LIMK1 (0.36) LIMK1MEN1KMT2AALDH1A1MAPT
SCHEMBL17425537 0.97 LIMK1 (0.36) LIMK1MEN1KMT2AALDH1A1MAPT
SCHEMBL17425714 0.97 LIMK1 (0.36) LIMK1MEN1KMT2AALDH1A1MAPT
SCHEMBL29985740 0.97 LIMK1 (0.36) LIMK1MEN1KMT2AALDH1A1MAPT
SCHEMBL29986676 0.97 LIMK1 (0.36) LIMK1MEN1KMT2AALDH1A1MAPT
SCHEMBL30021301 0.96 ALOX5 (0.36) LIMK1MEN1KMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230130110-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-27 US disclosed
US-20230130110-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-27 US disclosed
EP-4167707-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2023-04-19 EP disclosed
EP-3591728-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2022-12-14 EP disclosed
US-20210257554-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-08-19 US disclosed
US-11024811-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-06-01 US disclosed
EP-2966706-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2019-09-04 EP disclosed
US-20190259957-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-08-22 US disclosed
US-10297762-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-05-21 US disclosed
US-20170054087-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-02-23 US disclosed
US-20160093808-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-03-31 US disclosed
US-20160028021-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-01-28 US disclosed
US-20160028021-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-01-28 US disclosed
EP-2966706-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2016-01-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160028021-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OR10J3 LIMK1 115/4885MEN1 1828/4885KMT2A 3609/4885
US-20190259957-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SOD1, PIEZO1, L1CAM LIMK1 199/4885MEN1 452/4885KMT2A 3092/4885
US-20210257554-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SOD1, PIEZO1, L1CAM LIMK1 199/4885MEN1 452/4885KMT2A 3092/4885
US-11024811-B2 Organic electroluminescent materials and devices SOD1, PIEZO1, L1CAM LIMK1 199/4885MEN1 452/4885KMT2A 3092/4885
US-20230130110-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SOD1, PIEZO1, L1CAM LIMK1 199/4885MEN1 452/4885KMT2A 3092/4885
US-10297762-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, OR10J3 LIMK1 115/4885MEN1 1828/4885KMT2A 3609/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.