SCHEMBL17425569

SCHEMBL17425569

CC1(C)c2ccccc2-c2ccc(-c3cc(-c4nc(-c5ccccc5)nc(-c5ccccc5)n4)cc(-c4cccc5c4sc4ccccc45)c3)cc21

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.42
PRKDC P78527 1/20 0.34
PARP14 Q460N5 1/20 0.33
MAPT P10636 3/20 0.32
PDK2 Q15119 6/20 0.32
TNKS O95271 1/20 0.31
TNKS2 Q9H2K2 1/20 0.31
F9 P00740 1/20 0.31
MEN1 O00255 2/20 0.30
ALDH1A1 P00352 2/20 0.30
HPGD P15428 2/20 0.30
KMT2A Q03164 2/20 0.30
SLC9A1 P19634 1/20 0.30
ATM Q13315 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
KDM4E B2RXH2 1/20 0.30
LMNA P02545 1/20 0.30
GLA P06280 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30103496 1.00 ALOX5 (0.42) ALOX5PRKDCPARP14MAPTPDK2
SCHEMBL25405653 0.99 ALOX5 (0.41) ALOX5PRKDCPARP14MAPTPDK2
SCHEMBL15501966 0.98 ALOX5 (0.42) ALOX5PRKDCPARP14MAPTPDK2
SCHEMBL17425494 0.97 ALOX5 (0.41) ALOX5PRKDCPARP14MAPTPDK2
SCHEMBL30022890 0.97 ALOX5 (0.41) ALOX5PRKDCPARP14MAPTPDK2
SCHEMBL17425540 0.97 ALOX5 (0.41) ALOX5PRKDCPARP14MAPTPDK2
SCHEMBL15501987 0.97 ALOX5 (0.43) ALOX5PRKDCPARP14MAPTPDK2
SCHEMBL18904414 0.96 ALOX5 (0.43) ALOX5PRKDCPARP14MAPTPDK2
SCHEMBL15501922 0.93 ALOX5 (0.41) ALOX5PRKDCPARP14MAPTPDK2
SCHEMBL23024824 0.92 ALOX5 (0.38) ALOX5PRKDCPARP14MAPTPDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230130110-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-27 US disclosed
US-20230130110-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-27 US disclosed
EP-4167707-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2023-04-19 EP disclosed
EP-3591728-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2022-12-14 EP disclosed
US-20210257554-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-08-19 US disclosed
US-11024811-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-06-01 US disclosed
EP-2966706-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2019-09-04 EP disclosed
US-20190259957-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-08-22 US disclosed
US-10297762-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-05-21 US disclosed
US-20170054087-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-02-23 US disclosed
US-20160093808-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-03-31 US disclosed
US-20160028021-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-01-28 US disclosed
US-20160028021-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-01-28 US disclosed
EP-2966706-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2016-01-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160028021-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OR10J3 ALOX5 336/4885PRKDC 4297/4885PARP14 3661/4885
US-20190259957-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SOD1, PIEZO1, L1CAM ALOX5 3441/4885PRKDC 4114/4885PARP14 3614/4885
US-20210257554-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SOD1, PIEZO1, L1CAM ALOX5 3441/4885PRKDC 4114/4885PARP14 3614/4885
US-11024811-B2 Organic electroluminescent materials and devices SOD1, PIEZO1, L1CAM ALOX5 3441/4885PRKDC 4114/4885PARP14 3614/4885
US-20230130110-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SOD1, PIEZO1, L1CAM ALOX5 3441/4885PRKDC 4114/4885PARP14 3614/4885
US-10297762-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, OR10J3 ALOX5 336/4885PRKDC 4297/4885PARP14 3661/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.