Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 4/20 | 0.43 |
| ▸ | TDO2 | P48775 | 4/20 | 0.43 |
| ▸ | PLAU | P00749 | 2/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7129654 | 0.78 | IDO1 (0.54) | KDM4EALDH1A1MAPTTSHRIDO1 | |
| SCHEMBL8154614 | 0.77 | IDO1 (0.55) | KDM4EALDH1A1MAPTLMNAIDO1 | |
| SCHEMBL1114836 | 0.77 | CTDSP1 (0.53) | KDM4EALDH1A1USP2MAPTGAA | |
| Hydrochloric Acid SCHEMBL1114622 | 0.76 | CTDSP1 (0.52) | KDM4EALDH1A1USP2MAPTGAA | |
| SCHEMBL7496904 | 0.75 | IDO1 (0.52) | KDM4EALDH1A1USP2MAPTGAA | |
| SCHEMBL5751184 | 0.74 | ALDH1A1 (0.48) | KDM4EALDH1A1MAPTMAPK1PLAU | |
| SCHEMBL278576 | 0.74 | MAPT (0.67) | KDM4EALDH1A1MAPTTSHRMAPK1 | |
| SCHEMBL30380487 | 0.74 | MAPT (0.67) | KDM4EALDH1A1MAPTTSHRMAPK1 | |
| SCHEMBL21255664 | 0.73 | TUBB4A (0.51) | KDM4EMAPTGAACYP19A1NQO2 | |
| SCHEMBL3631528 | 0.73 | NQO1 (0.64) | KDM4EALDH1A1MAPTMAPK1NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101203500-B | Substituted arylamine compounds and their use as 5-HT6Use of modulators | GALENEA CORP | 2013-08-21 | — | — | CN | disclosed |
| EP-2387564-A1 | BENZO ÝC¨PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | Rutgers, The State University of New Jersey (US) | 2011-11-23 | — | — | EP | disclosed |
| US-8037884-B2 | Modular system for patient positioning during medical procedures | ALLEN MEDICAL SYSTEMS, INC. (US) | 2011-10-18 | — | — | US | disclosed |
| WO-2010083436-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2010-07-22 | — | — | WO | disclosed |
| CN-101203500-A | Substituted arylamine compounds and their use as 5-HT6Use of modulators | EPIX DELAWARE INC (US) | 2008-06-18 | — | — | CN | disclosed |
| CN-1046723-C | Tetracyclic compounds as dopamine agonists | ABBOTT LAB (US) | 1999-11-24 | — | — | CN | disclosed |
| CN-1124489-A | Tetracyclic compounds as dopamine agonists | ABBOTT LAB (US) | 1996-06-12 | — | — | CN | disclosed |