SCHEMBL17425633

SCHEMBL17425633

c1ccc(-c2cccc(-c3cccc4c3sc3ccc(-c5cccc(-c6nc(-c7ccccc7)nc(-c7ccccc7)n6)c5)cc34)c2)cc1

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.49
LIMK1 P53667 3/20 0.43
PIM3 Q86V86 3/20 0.40
PIM1 P11309 3/20 0.38
PIM2 Q9P1W9 2/20 0.38
MAP3K8 P41279 4/20 0.36
ROCK1 Q13464 1/20 0.36
PRKDC P78527 1/20 0.35
ADORA2A P29274 1/20 0.35
ADORA1 P30542 1/20 0.35
MEN1 O00255 1/20 0.35
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
KMT2A Q03164 1/20 0.35
PIK3CA P42336 1/20 0.35
PI4KA P42356 1/20 0.35
PI4KB Q9UBF8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17425610 1.00 ALOX5 (0.49) ALOX5LIMK1PIM3PIM1PIM2
SCHEMBL24216224 1.00 ALOX5 (0.49) ALOX5LIMK1PIM3PIM1PIM2
SCHEMBL25645908 0.97 ALOX5 (0.46) ALOX5LIMK1PIM3PIM1PIM2
SCHEMBL17425636 0.97 ALOX5 (0.46) ALOX5LIMK1PIM3PIM1PIM2
SCHEMBL25851907 0.97 ALOX5 (0.46) ALOX5LIMK1PIM3PIM1PIM2
SCHEMBL22329223 0.97 ALOX5 (0.51) ALOX5LIMK1PIM3PIM1PIM2
SCHEMBL22701818 0.96 ALOX5 (0.52) ALOX5LIMK1PIM3PIM1PIM2
SCHEMBL18216736 0.96 ALOX5 (0.45) ALOX5LIMK1PIM3PIM1PIM2
SCHEMBL17425654 0.96 ALOX5 (0.47) ALOX5LIMK1PIM3PIM1PIM2
SCHEMBL22701875 0.95 ALOX5 (0.51) ALOX5LIMK1PIM3PIM1PIM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11515484-B2 Heterocyclic compound and organic light emitting element comprising same LT MATERIALS CO., LTD. (KR) 2022-11-29 US disclosed
US-20200266355-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME HEESUNG MATERIAL LTD. (KR) 2020-08-20 US disclosed
EP-3683217-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LT Materials Co., Ltd. (KR) 2020-07-22 EP disclosed
US-20170054087-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-02-23 US disclosed
US-20160093808-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-03-31 US disclosed
US-20160028021-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-01-28 US disclosed
EP-2966706-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2016-01-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11515484-B2 Heterocyclic compound and organic light emitting element comprising same CRY1, CRY2, CYP1A1 ALOX5 751/4885LIMK1 547/4885PIM3 2903/4885
US-20160028021-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OR10J3 ALOX5 336/4885LIMK1 115/4885PIM3 2565/4885
US-20200266355-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME CRY1, CRY2, CYP1A1 ALOX5 751/4885LIMK1 547/4885PIM3 2903/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.