SCHEMBL17425906

SCHEMBL17425906

OCOC=Cc1ccc(Br)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 3/20 0.38
ALDH1A1 P00352 3/20 0.38
KDM4E B2RXH2 1/20 0.38
HPGD P15428 1/20 0.38
RAB9A P51151 1/20 0.38
MAPT P10636 4/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
CYP2C9 P11712 2/20 0.38
CYP2D6 P10635 2/20 0.38
CYP3A4 P08684 1/20 0.38
TUBB4A P04350 1/20 0.38
TUBB P07437 1/20 0.38
TUBA3C P0DPH7 1/20 0.38
TUBA1B P68363 1/20 0.38
TUBA4A P68366 1/20 0.38
TUBB4B P68371 1/20 0.38
TUBB3 Q13509 1/20 0.38
TUBB2A Q13885 1/20 0.38
TUBB8 Q3ZCM7 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14780855 0.79 CYP2C19 (0.38) CYP2C19ALDH1A1KDM4EHPGDRAB9A
SCHEMBL902965 0.78 MAOB (0.44) ALDH1A1RAB9AMAPTCYP2C9CYP2D6
SCHEMBL8319087 0.75 CYP2C19 (0.45) CYP2C19ALDH1A1KDM4EHPGDRAB9A
SCHEMBL119646 0.71 ALDH1A1 (0.52) CYP2C19ALDH1A1KDM4EHPGDRAB9A
SCHEMBL9268881 0.71 TUBB4A (0.50) CYP2C19ALDH1A1KDM4EHPGDRAB9A
SCHEMBL7132075 0.71 TUBB4A (0.50) CYP2C19ALDH1A1KDM4EHPGDRAB9A
SCHEMBL119647 0.71 ALDH1A1 (0.52) CYP2C19ALDH1A1KDM4EHPGDRAB9A
SCHEMBL1882464 0.71 ALDH1A1 (0.61) CYP2C19ALDH1A1KDM4EHPGDRAB9A
SCHEMBL391121 0.71 ALDH1A1 (0.61) CYP2C19ALDH1A1KDM4EHPGDRAB9A
SCHEMBL9679616 0.71 ALDH1A1 (0.61) CYP2C19ALDH1A1KDM4EHPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2182405-B1 LIQUID CRYSTAL ALIGNING AGENT, METHOD FOR PRODUCING LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY DEVICE JSR CORP (JP) 2016-01-13 EP disclosed