Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 7/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17425975 | 0.89 | MET (0.44) | METKDM4CP2RX3 | |
| SCHEMBL16882542 | 0.84 | MET (0.46) | MET | |
| SCHEMBL2177639 | 0.83 | MET (0.54) | MET | |
| SCHEMBL29773372 | 0.76 | MET (0.50) | MET | |
| SCHEMBL12483227 | 0.76 | MET (0.50) | MET | |
| SCHEMBL2178001 | 0.75 | MET (0.48) | MET | |
| SCHEMBL12690022 | 0.74 | MET (0.52) | MET | |
| SCHEMBL22475682 | 0.73 | MET (0.42) | MET | |
| SCHEMBL2177521 | 0.72 | MET (0.50) | MET | |
| SCHEMBL16882492 | 0.71 | MET (0.53) | MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2966075-A1 | CERTAIN TRIAZOLOPYRIDINES, COMPOSITIONS THEREOF AND THEIR USE IN THE TREATMENT OF CANCER. | Hutchison Medipharma Limited (CN) | 2016-01-13 | — | — | EP | disclosed |