SCHEMBL17426014

SCHEMBL17426014

CC1(C)c2cc3ccccc3cc2N(c2ccc(-c3ccccc3)cc2)c2ccc3cc(C=C4C(=O)c5cc6ccccc6cc5C4=O)ccc3c21

nearest known ligand 0.34

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PDE6D O43924 1/20 0.34
BCL2 P10415 1/20 0.34
BAX Q07812 1/20 0.34
BCL2L1 Q07817 1/20 0.34
MAPT P10636 4/20 0.33
KDM4E B2RXH2 3/20 0.33
ALDH1A1 P00352 3/20 0.33
GAA P10253 1/20 0.33
MEN1 O00255 3/20 0.31
KMT2A Q03164 3/20 0.31
PTPN1 P18031 1/20 0.30
HPGD P15428 1/20 0.30
CDC25A P30304 1/20 0.30
CDC25B P30305 1/20 0.30
CTDSP1 Q9GZU7 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
RET P07949 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17426006 0.94 MAPT (0.36) BCL2BAXBCL2L1MAPTKDM4E
SCHEMBL17426032 0.94 MAPT (0.33) PDE6DBCL2BAXBCL2L1MAPT
SCHEMBL18267287 0.93 BCL2 (0.35) PDE6DBCL2BAXBCL2L1MAPT
SCHEMBL17426031 0.93 MAPT (0.34) BCL2BAXBCL2L1MAPTKDM4E
SCHEMBL15118353 0.92 PDE6D (0.34) PDE6DBCL2BAXBCL2L1MAPT
SCHEMBL17426028 0.92 ERO1A (0.36) BCL2BAXBCL2L1MAPTKDM4E
SCHEMBL17426047 0.92 ALDH1A1 (0.37) BCL2BAXBCL2L1MAPTKDM4E
SCHEMBL17426041 0.91 PGR (0.35) MAPTKDM4EALDH1A1GAAMEN1
SCHEMBL17778894 0.90 KMT2A (0.41) MAPTKDM4EALDH1A1MEN1KMT2A
SCHEMBL17773922 0.89 ALDH1A1 (0.32) MAPTKDM4EALDH1A1GAAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160013424-A1 PHOTOELECTRIC CONVERSION ELEMENT AND METHOD OF USING SAME, OPTICAL SENSOR AND IMAGE SENSOR FUJIFILM CORPORATION (JP) 2016-01-14 US disclosed
US-20160013424-A1 PHOTOELECTRIC CONVERSION ELEMENT AND METHOD OF USING SAME, OPTICAL SENSOR AND IMAGE SENSOR FUJIFILM CORPORATION (JP) 2016-01-14 US disclosed