SCHEMBL17426430

SCHEMBL17426430

Clc1ccc2[nH]c3ccc4c5ccc6c(c7ccccc7n6-c6ccccc6)c5oc4c3c2c1

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.43
KMT2A Q03164 4/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
LMNA P02545 1/20 0.43
KDM4E B2RXH2 2/20 0.37
ATM Q13315 1/20 0.37
ALDH1A1 P00352 2/20 0.37
POLB P06746 1/20 0.37
TSHR P16473 1/20 0.37
BRCA1 P38398 1/20 0.37
HSD17B10 Q99714 1/20 0.37
MAT2A P31153 6/20 0.36
ADORA3 P0DMS8 1/20 0.35
GAA P10253 1/20 0.34
RXFP1 Q9HBX9 1/20 0.34
PRMT5 O14744 1/20 0.34
EDNRA P25101 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16484349 0.88 L3MBTL1 (0.42) MEN1KMT2AL3MBTL1LMNAKDM4E
SCHEMBL17426431 0.88 L3MBTL1 (0.45) MEN1KMT2AL3MBTL1LMNAKDM4E
SCHEMBL19501152 0.87 MEN1 (0.50) MEN1KMT2AL3MBTL1LMNAKDM4E
SCHEMBL16485513 0.84 L3MBTL1 (0.40) MEN1KMT2AL3MBTL1LMNAKDM4E
SCHEMBL16483875 0.83 GABRP (0.38) MEN1KMT2AL3MBTL1KDM4EATM
SCHEMBL11933013 0.80 L3MBTL1 (0.57) MEN1KMT2AL3MBTL1KDM4EATM
SCHEMBL19501156 0.80 MEN1 (0.48) MEN1KMT2AL3MBTL1LMNAKDM4E
SCHEMBL23436929 0.79 ALDH1A1 (0.40) MEN1KMT2ALMNAALDH1A1POLB
SCHEMBL4554400 0.79 AHR (0.48) MEN1KMT2AL3MBTL1LMNAKDM4E
SCHEMBL25491703 0.79 MEN1 (0.41) MEN1KMT2AL3MBTL1LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9842996-B2 Amine compound having hetero-fused ring and organic electroluminescent element using amine compound IDEMITSU KOSAN CO., LTD. (JP) 2017-12-12 US disclosed
US-9842996-B2 Amine compound having hetero-fused ring and organic electroluminescent element using amine compound IDEMITSU KOSAN CO., LTD. (JP) 2017-12-12 US disclosed
US-20160013419-A1 AMINE COMPOUND HAVING HETERO-FUSED RING AND ORGANIC ELECTROLUMINESCENT ELEMENT USING AMINE COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2016-01-14 US disclosed
US-20160013419-A1 AMINE COMPOUND HAVING HETERO-FUSED RING AND ORGANIC ELECTROLUMINESCENT ELEMENT USING AMINE COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2016-01-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160013419-A1 AMINE COMPOUND HAVING HETERO-FUSED RING AND ORGANIC ELECTROLUMINESCENT ELEMENT USING AMINE COMPOUND CTCF, SAT1, TEAD2 MEN1 192/4885KMT2A 163/4885L3MBTL1 2674/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.