Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET2 | Q6N021 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.31 |
| ▸ | HMGCR | P04035 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1227419 | 0.83 | ALDH1A1 (0.39) | TET2ALDH1A1 | |
| SCHEMBL11920344 | 0.83 | ALDH1A1 (0.44) | TET2ALDH1A1 | |
| SCHEMBL26501514 | 0.80 | TET2 (0.45) | TET2ALDH1A1CYP2D6TSHRCYP2C19 | |
| SCHEMBL11032460 | 0.80 | ALDH1A1 (0.44) | TET2ALDH1A1CYP2D6TSHRCYP2C19 | |
| SCHEMBL11851950 | 0.78 | TSHR (0.46) | TET2ALDH1A1CYP2D6TSHRCYP2C19 | |
| SCHEMBL27856262 | 0.78 | ALDH1A1 (0.42) | TET2ALDH1A1CYP2D6TSHRCYP2C19 | |
| SCHEMBL2524423 | 0.78 | TET2 (0.64) | TET2ALDH1A1CYP2D6TSHRCYP2C19 | |
| SCHEMBL28159544 | 0.77 | ALDH1A1 (0.41) | TET2ALDH1A1CYP2D6TSHRCYP2C19 | |
| SCHEMBL4257393 | 0.76 | TET2 (0.35) | TET2 | |
| SCHEMBL21373151 | 0.75 | ALDH1A1 (0.39) | TET2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9907733-B2 | Dental compositions comprising addition-fragmentation agents | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2018-03-06 | — | — | US | disclosed |
| US-20160008234-A1 | DENTAL COMPOSITIONS COMPRISING ADDITION-FRAGMENTATION AGENTS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-01-14 | — | — | US | disclosed |
| US-20160008234-A1 | DENTAL COMPOSITIONS COMPRISING ADDITION-FRAGMENTATION AGENTS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-01-14 | — | — | US | disclosed |
| CN-1389451-A | Allyl chain transfer agent | COMMW SCIENT IND RES ORG (AU) | 2003-01-08 | — | — | CN | disclosed |
| CN-1082965-C | Allyl chain transfer agent | COMMW SCIENT IND RES ORG (AU) | 2002-04-17 | — | — | CN | disclosed |
| CN-1138320-A | Allyl chain transfer agent | COMMW SCIENT IND RES ORG (AU) | 1996-12-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160008234-A1 | DENTAL COMPOSITIONS COMPRISING ADDITION-FRAGMENTATION AGENTS | RAD51, TUBA8, ERCC4 | TET2 2559/4885ALDH1A1 2749/4885CYP2D6 4400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.