Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TET2 | Q6N021 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | SI | P14410 | 1/20 | 0.30 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11920345 | 0.83 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL1227419 | 0.83 | ALDH1A1 (0.39) | ALDH1A1TET2 | |
| SCHEMBL17426460 | 0.83 | TET2 (0.41) | ALDH1A1TET2 | |
| SCHEMBL7128010 | 0.81 | ALDH1A1 (0.46) | ALDH1A1TET2GAAMAPTMGAM | |
| SCHEMBL11032460 | 0.80 | ALDH1A1 (0.44) | ALDH1A1TET2 | |
| SCHEMBL27856262 | 0.78 | ALDH1A1 (0.42) | ALDH1A1TET2 | |
| SCHEMBL28159544 | 0.77 | ALDH1A1 (0.41) | ALDH1A1TET2 | |
| SCHEMBL16018846 | 0.75 | ALDH1A1 (0.39) | ALDH1A1TET2 | |
| SCHEMBL21373151 | 0.75 | ALDH1A1 (0.39) | ALDH1A1TET2 | |
| SCHEMBL2468506 | 0.74 | ALDH1A1 (0.42) | ALDH1A1TET2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230323151-A1 | IMIDE ADDITION-FRAGMENTATION AGENTS | 3M INNOVATIVE PROPERTIES COMPANY | 2023-10-12 | — | — | US | disclosed |
| US-10022306-B2 | Dental compositions comprising a fatty mono(meth)acrylate | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2018-07-17 | — | — | US | disclosed |
| US-9907733-B2 | Dental compositions comprising addition-fragmentation agents | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2018-03-06 | — | — | US | disclosed |
| US-20170210693-A1 | ADDITION-FRAGMENTATION AGENTS | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2017-07-27 | — | — | US | disclosed |
| US-20160361238-A1 | DENTAL COMPOSITIONS COMPRISING A FATTY MONO(METH)ACRYLATE | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2016-12-15 | — | — | US | disclosed |
| US-9433563-B2 | Dental compositions comprising a fatty mono(meth)acrylate | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2016-09-06 | — | — | US | disclosed |
| US-9403966-B2 | Addition-fragmentation agents | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-08-02 | — | — | US | disclosed |
| US-9320685-B2 | Dental compositions comprising ethylenically unsaturated addition-fragmentation agent | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-04-26 | — | — | US | disclosed |
| US-20160008234-A1 | DENTAL COMPOSITIONS COMPRISING ADDITION-FRAGMENTATION AGENTS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-01-14 | — | — | US | disclosed |
| US-20150238389-A1 | DENTAL COMPOSITIONS COMPRISING ETHYLENICALLY UNSATURATED ADDITION-FRAGMENTATION AGENT | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2015-08-27 | — | — | US | disclosed |
| US-20150203658-A1 | ADDITION-FRAGMENTATION AGENTS | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2015-07-23 | — | — | US | disclosed |
| US-9056043-B2 | Dental compositions comprising ethylenically unsaturated addition-fragmentation agent | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-06-16 | — | — | US | disclosed |
| US-8980969-B2 | Addition-fragmentation agents | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-03-17 | — | — | US | disclosed |
| US-20140206788-A1 | ADDITION-FRAGMENTATION AGENTS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-07-24 | — | — | US | disclosed |
| US-20120208965-A1 | ADDITION-FRAGMENTATION AGENTS | 3M INNOVATIVE PROPERTIES COMPANY | 2012-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120208965-A1 | ADDITION-FRAGMENTATION AGENTS | NR4A1, PARP14, MTX1 | ALDH1A1 3630/4885TET2 2892/4885GAA 3473/4885 |
| US-20160361238-A1 | DENTAL COMPOSITIONS COMPRISING A FATTY MONO(METH)ACRYLATE | MMAB, ELOVL5, ELOVL1 | ALDH1A1 1066/4885TET2 157/4885GAA 4252/4885 |
| US-20170210693-A1 | ADDITION-FRAGMENTATION AGENTS | NR4A1, PARP14, MTX1 | ALDH1A1 3630/4885TET2 2892/4885GAA 3473/4885 |
| US-20150238389-A1 | DENTAL COMPOSITIONS COMPRISING ETHYLENICALLY UNSATURATED ADDITION-FRAGMENTATION AGENT | NR4A1, RXRG, RXRA | ALDH1A1 4052/4885TET2 3281/4885GAA 3893/4885 |
| US-10022306-B2 | Dental compositions comprising a fatty mono(meth)acrylate | MMAB, ELOVL5, ELOVL1 | ALDH1A1 1066/4885TET2 157/4885GAA 4252/4885 |
| US-20160008234-A1 | DENTAL COMPOSITIONS COMPRISING ADDITION-FRAGMENTATION AGENTS | RAD51, TUBA8, ERCC4 | ALDH1A1 2749/4885TET2 2559/4885GAA 777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.