Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CTSD | P07339 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19084159 | 0.87 | NAAA (0.41) | GAACTSDNAAA | |
| SCHEMBL17426991 | 0.86 | GAA (0.43) | GAACTSDBACE1NAAA | |
| SCHEMBL19633453 | 0.85 | GAA (0.41) | GAACTSDBACE1 | |
| SCHEMBL19089218 | 0.84 | GAA (0.46) | GAACTSDBACE1NAAA | |
| SCHEMBL19628388 | 0.82 | GAA (0.49) | GAACTSDNAAA | |
| SCHEMBL17427170 | 0.81 | GAA (0.37) | GAACTSDNAAA | |
| SCHEMBL17426989 | 0.81 | KMT2A (0.44) | GAANAAA | |
| SCHEMBL19091499 | 0.81 | GAA (0.41) | GAACTSDBACE1NAAA | |
| SCHEMBL17898647 | 0.80 | GAA (0.47) | GAACTSDNAAA | |
| SCHEMBL17426932 | 0.80 | GAA (0.36) | GAACTSDNAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170273303-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | CORTEVA AGRISCIENCE LLC | 2017-09-28 | — | — | US | disclosed |
| US-20170273303-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | CORTEVA AGRISCIENCE LLC | 2017-09-28 | — | — | US | disclosed |
| US-9686984-B2 | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2017-06-27 | — | — | US | disclosed |
| US-9686984-B2 | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2017-06-27 | — | — | US | disclosed |
| US-20160007602-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC | 2016-01-14 | — | — | US | disclosed |
| US-20160007602-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC | 2016-01-14 | — | — | US | disclosed |
| WO-2016007531-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2016-01-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170273303-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | CYP4F12, CYP1A2, FKBP2 | GAA 1303/4885CTSD 1352/4885BACE1 2196/4885 |
| US-20160007602-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | CYP4F12, CYP1A2, FKBP2 | GAA 1303/4885CTSD 1352/4885BACE1 2196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.