Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CTSD | P07339 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17899063 | 0.87 | GAA (0.39) | GAACTSDBACE1BTK | |
| SCHEMBL17898809 | 0.86 | GAA (0.39) | GAACTSDBACE1 | |
| SCHEMBL19091088 | 0.85 | GAA (0.49) | GAACTSDNFKB1NFKB2RELA | |
| SCHEMBL19084175 | 0.85 | GAA (0.43) | GAANFKB1NFKB2RELABTK | |
| SCHEMBL17898811 | 0.85 | GAA (0.38) | GAACTSDBACE1KMT2AL3MBTL1 | |
| SCHEMBL17427147 | 0.84 | GAA (0.44) | GAACTSDBACE1NAAA | |
| SCHEMBL17899064 | 0.83 | GAA (0.36) | GAACTSDKMT2AL3MBTL1 | |
| SCHEMBL19091547 | 0.83 | GAA (0.47) | GAACTSDNFKB1NFKB2RELA | |
| SCHEMBL19091107 | 0.83 | GAA (0.43) | GAACTSDNFKB1NFKB2RELA | |
| SCHEMBL19091499 | 0.81 | GAA (0.41) | GAACTSDBACE1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017116949-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2017-07-06 | — | — | WO | disclosed |