Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMURF1 | Q9HCE7 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17430384 | 0.87 | POLB (0.41) | POLBMAPTFLT1KDRMET | |
| SCHEMBL17430007 | 0.86 | MET (0.41) | POLBMETAXL | |
| SCHEMBL17427383 | 0.83 | POLB (0.42) | POLBMAPTTP53SMN1; SMN2MET | |
| SCHEMBL16022006 | 0.83 | POLB (0.39) | POLBL3MBTL1TP53SMN1; SMN2MET | |
| SCHEMBL17427393 | 0.83 | POLB (0.49) | POLBMAPTL3MBTL1SMURF1 | |
| SCHEMBL17427397 | 0.83 | POLB (0.44) | POLBL3MBTL1SMN1; SMN2MET | |
| SCHEMBL17427386 | 0.81 | POLB (0.42) | POLBMAPTMETAXL | |
| SCHEMBL17430275 | 0.81 | IKBKE (0.40) | POLBMAPTTP53SMN1; SMN2 | |
| SCHEMBL17427455 | 0.81 | POLB (0.41) | POLBMAPTTP53METAXL | |
| SCHEMBL18590179 | 0.80 | MAPT (0.43) | POLBMAPTFLT1KDRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160009693-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2016-01-14 | — | — | US | disclosed |
| US-20160009693-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2016-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160009693-A1 | HERBICIDAL COMPOUNDS | DDT, HAX1, CYP4X1 | POLB 4093/4885MAPT 4184/4885L3MBTL1 1611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.