Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 6/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17427403 | 0.83 | POLB (0.39) | POLBSMN1; SMN2TP53L3MBTL1MET | |
| SCHEMBL17427393 | 0.82 | POLB (0.49) | POLBTDP1ALDH1A1L3MBTL1 | |
| SCHEMBL16022000 | 0.82 | MET (0.44) | POLBSMN1; SMN2METAXL | |
| SCHEMBL17222514 | 0.82 | POLB (0.51) | POLBTDP1ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL17427363 | 0.81 | RAB9A (0.42) | POLBTDP1ALDH1A1NR3C1THRB | |
| SCHEMBL17427411 | 0.81 | POLB (0.45) | POLBTDP1ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL17430284 | 0.81 | POLB (0.42) | POLBALDH1A1TSHRSMN1; SMN2TP53 | |
| SCHEMBL16022023 | 0.80 | POLB (0.41) | POLBALDH1A1SMN1; SMN2MET | |
| SCHEMBL17427474 | 0.78 | POLB (0.39) | POLBTHRBTP53METAXL | |
| SCHEMBL16022057 | 0.78 | POLB (0.42) | POLBTHRBTP53METAXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160009693-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2016-01-14 | — | — | US | disclosed |
| US-20160009693-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2016-01-14 | — | — | US | disclosed |
| WO-2014135654-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2014-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160009693-A1 | HERBICIDAL COMPOUNDS | DDT, HAX1, CYP4X1 | POLB 4093/4885TDP1 1722/4885ALDH1A1 79/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.