Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 2/20 | 0.38 |
| ▸ | MERTK | Q12866 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17427480 | 0.94 | NPC1 (0.46) | HPGDCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL16022022 | 0.81 | AXL (0.40) | ALDH1A1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL16034176 | 0.77 | KDM4E (0.68) | HPGDCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL16022040 | 0.73 | NOTUM (0.56) | ALDH1A1LMNAKDM4ETDP1SMN1; SMN2 | |
| SCHEMBL17427415 | 0.72 | SMN1; SMN2 (0.47) | HPGDCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL17427479 | 0.72 | POLB (0.47) | HPGDCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL17427392 | 0.72 | POLB (0.43) | ALDH1A1LMNAKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL16022039 | 0.72 | BAZ2B (0.47) | HPGDALDH1A1KDM4ETDP1SMN1; SMN2 | |
| SCHEMBL17427388 | 0.69 | LMNA (0.39) | CYP1A2CYP2C19ALDH1A1LMNAKDM4E | |
| SCHEMBL16022056 | 0.69 | LMNA (0.39) | HPGDCYP1A2CYP2C19ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160009693-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2016-01-14 | — | — | US | disclosed |
| US-20160009693-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2016-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160009693-A1 | HERBICIDAL COMPOUNDS | DDT, HAX1, CYP4X1 | HPGD 1834/4885CYP1A2 20/4885CYP2C9 126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.