Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 5/20 | 0.40 |
| ▸ | MERTK | Q12866 | 4/20 | 0.40 |
| ▸ | MET | P08581 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17427477 | 0.87 | MET (0.38) | AXLMETKMT2ALMNATYRO3 | |
| SCHEMBL17427478 | 0.84 | LMNA (0.39) | AXLMETKMT2ALMNAGAA | |
| SCHEMBL17427480 | 0.82 | NPC1 (0.46) | AXLMERTKMETKMT2ALMNA | |
| SCHEMBL17427481 | 0.81 | HPGD (0.53) | AXLMERTKMETLMNAGAA | |
| SCHEMBL16022040 | 0.78 | NOTUM (0.56) | KMT2ALMNANOTUMNPC1RAB9A | |
| SCHEMBL16022039 | 0.72 | BAZ2B (0.47) | NOTUMALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL17427486 | 0.70 | CTDSP1 (0.39) | KMT2ANPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL17427475 | 0.69 | TYRO3 (0.41) | AXLMERTKMETKMT2ATYRO3 | |
| SCHEMBL17427476 | 0.69 | MERTK (0.38) | AXLMERTKMETLMNANOTUM | |
| SCHEMBL17427479 | 0.69 | POLB (0.47) | AXLMETKMT2ALMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160009693-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2016-01-14 | — | — | US | disclosed |
| US-20160009693-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2016-01-14 | — | — | US | disclosed |
| WO-2014135654-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2014-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160009693-A1 | HERBICIDAL COMPOUNDS | DDT, HAX1, CYP4X1 | AXL 3850/4885MERTK 4541/4885MET 3504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.