Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.45 |
| ▸ | EEF2K | O00418 | 1/20 | 0.36 |
| ▸ | PROKR1 | Q8TCW9 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8228221 | 0.83 | ADORA2A (0.38) | ADORA2AADORA1PROKR1GAAADORA3 | |
| SCHEMBL8784955 | 0.83 | NAPRT (0.38) | ADORA2AADORA1PROKR1GAAADORA3 | |
| SCHEMBL29002489 | 0.81 | ADORA2A (0.42) | ADORA2AADORA1GAAADORA3KDM4E | |
| SCHEMBL2076844 | 0.80 | L3MBTL1 (0.40) | ADORA2AADORA1EEF2KIKBKBL3MBTL1 | |
| SCHEMBL1833232 | 0.79 | ADORA2A (0.49) | ADORA2AADORA1GAAADORA3KDM4E | |
| SCHEMBL1224892 | 0.79 | GAA (0.50) | ADORA2AADORA1PROKR1GAAALDH1A1 | |
| SCHEMBL6600155 | 0.79 | SMN1; SMN2 (0.39) | ADORA2AADORA1PROKR1GAAADORA3 | |
| SCHEMBL21117539 | 0.79 | GAA (0.46) | ADORA2AADORA1GAAALDH1A1L3MBTL1 | |
| SCHEMBL11564068 | 0.79 | F2 (0.52) | ADORA2AADORA1PROKR1GAAADORA3 | |
| SCHEMBL8799072 | 0.78 | ADORA2A (0.41) | ADORA2AADORA1GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023185986-A1 | BCL-XL INHIBITORS | BEIGENE , LTD. (KY) | 2023-10-05 | — | — | WO | disclosed |
| US-20130303533-A1 | AZOLOPYRIDINE AND AZOLOPYRIMIDINE COMPOUNDS AND METHODS OF USE THEREOF | AMBIT BIOSCIENCES CORPORATION (US) | 2013-11-14 | — | — | US | disclosed |
| EP-2611809-A1 | AZOLOPYRIDINE AND AZOLOPYRIMIDINE COMPOUNDS AND METHODS OF USE THEREOF | Ambit Biosciences Corporation (US) | 2013-07-10 | — | — | EP | disclosed |
| WO-2012030924-A1 | AZOLOPYRIDINE AND AZOLOPYRIMIDINE COMPOUNDS AND METHODS OF USE THEREOF | AMBIT BIOSCIENCES CORPORATION (US) | 2012-03-08 | — | — | WO | disclosed |
| EP-0623113-B1 | PYRAZOLE CARBOXANILIDE FUNGICIDES | MONSANTO CO (US) | 1997-03-05 | — | — | EP | disclosed |
| EP-0623113-A1 | PYRAZOLE CARBOXANILIDE FUNGICIDES. | MONSANTO CO (US) | 1994-11-09 | — | — | EP | disclosed |
| US-5223526-A | For plants | MONSANTO COMPANY (US) | 1993-06-29 | — | — | US | disclosed |
| WO-1993011117-A1 | PYRAZOLE CARBOXANILIDE FUNGICIDES | MONSANTO COMPANY (US) | 1993-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130303533-A1 | AZOLOPYRIDINE AND AZOLOPYRIMIDINE COMPOUNDS AND METHODS OF USE THEREOF | JAK3, JAK2, JAK1 | ADORA2A 1933/4885ADORA1 3035/4885EEF2K 709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.