Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 3/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | PTPRB | P23467 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | FAP | Q12884 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL683494 | 1.00 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2DPP4DPP7IDO1 | |
| Bromide SCHEMBL468370 | 0.99 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2DPP4DPP7IDO1 | |
| Bromide SCHEMBL17419382 | 0.99 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2DPP4DPP7IDO1 | |
| Bromide SCHEMBL21485485 | 0.99 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2DPP4DPP7IDO1 | |
| Bromide SCHEMBL28828062 | 0.99 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2DPP4DPP7IDO1 | |
| SCHEMBL8556382 | 0.83 | PTPRB (0.41) | ALDH1A1SMN1; SMN2IDO1PTPRBMAPT | |
| SCHEMBL500399 | 0.81 | PTPRB (0.44) | ALDH1A1SMN1; SMN2DPP4DPP7DPP8 | |
| SCHEMBL468264 | 0.81 | PTPRB (0.44) | ALDH1A1SMN1; SMN2DPP4DPP7DPP8 | |
| SCHEMBL468265 | 0.80 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2DPP4DPP7DPP8 | |
| SCHEMBL27751526 | 0.79 | EPHX1 (0.38) | ALDH1A1SMN1; SMN2DPP4DPP7IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160008327-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR PREVENTING METASASIS OF CANCER CELLS | EyePoint, Inc. | 2016-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160008327-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR PREVENTING METASASIS OF CANCER CELLS | TSG101, MMP8, EPCAM | ALDH1A1 748/4885SMN1; SMN2 2100/4885DPP4 2305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.