SCHEMBL17430254

SCHEMBL17430254

C=Cc1ccc2c(c1)C(C)(C)c1cc(-c3cc(-c4ccc5c(c4)C(C)(C)c4cc(C=C)ccc4-5)c4ccc5c(-c6ccc7c(c6)C(C)(C)c6cc(CCCc8cc(CO)c(O)c(CO)c8)ccc6-7)cc(-c6ccc7c(c6)C(C)(C)c6cc(CCCc8cc(CO)c(O)c(CO)c8)ccc6-7)c6ccc3c4c65)ccc1-2

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ ALK Q9UM73 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16020400 0.90 — —
SCHEMBL17913980 0.88 MPL (0.32) —
SCHEMBL16025225 0.88 ALK (0.33) ALK
SCHEMBL17427333 0.88 SHBG (0.33) —
SCHEMBL17578348 0.84 PDK2 (0.33) —
SCHEMBL16020499 0.83 — —
SCHEMBL16017985 0.78 FFAR4 (0.30) —
SCHEMBL16025171 0.77 MPL (0.35) —
SCHEMBL17427322 0.77 PDK2 (0.36) —
SCHEMBL17427311 0.77 PDK2 (0.36) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9740117-B2 Electrophotographic photosensitive member, process cartridge, electrophotographic apparatus, and condensed polycyclic aromatic compound CANON KABUSHIKI KAISHA (JP) 2017-08-22 — — US disclosed
US-20160011529-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, ELECTROPHOTOGRAPHIC APPARATUS, AND CONDENSED POLYCYCLIC AROMATIC COMPOUND CANON KABUSHIKI KAISHA (JP) 2016-01-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160011529-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, ELECTROPHOTOGRAPHIC APPARATUS, AND CONDENSED POLYCYCLIC AROMATIC COMPOUND SLC18A1, TRPA1, PAH ALK 701/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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