Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | LPL | P06858 | 1/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7147959 | 0.80 | ALDH1A1 (0.56) | ALDH1A1PLK1EGFRSMN1; SMN2LMNA | |
| SCHEMBL17430659 | 0.79 | BCL2 (0.46) | ALDH1A1SMN1; SMN2LMNAHPGDTP53 | |
| SCHEMBL564730 | 0.78 | ALDH1A1 (0.54) | ALDH1A1PLK1EGFRSMN1; SMN2LMNA | |
| SCHEMBL156207 | 0.78 | ALDH1A1 (0.63) | ALDH1A1PLK1LMNAHPGDHSD17B10 | |
| Bicarbonate SCHEMBL9816065 | 0.76 | ALDH1A1 (0.71) | ALDH1A1PLK1EGFRSMN1; SMN2LPL | |
| Bicarbonate SCHEMBL29051240 | 0.76 | ALDH1A1 (0.71) | ALDH1A1PLK1EGFRSMN1; SMN2LPL | |
| SCHEMBL7149195 | 0.76 | ALDH1A1 (0.52) | ALDH1A1PLK1EGFRSMN1; SMN2LMNA | |
| SCHEMBL38652216 | 0.76 | ALDH1A1 (0.52) | ALDH1A1PLK1EGFRSMN1; SMN2LMNA | |
| SCHEMBL155192 | 0.76 | ALDH1A1 (0.52) | ALDH1A1PLK1EGFRSMN1; SMN2LMNA | |
| SCHEMBL2702012 | 0.76 | CA2 (0.64) | ALDH1A1PLK1SMN1; SMN2CA2PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016005474-A1 | SITE SELECTIVE CONJUGATION OF AN OLIGONUCLEOTIDE CONJUGATE OR A SMALL MOLECULE TO A METAL BINDING PROTEIN | AFFYCON APS (DK) | 2016-01-14 | — | — | WO | disclosed |