Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1515871 | 0.82 | AKR1B1 (0.58) | BCL2LMNAHTTMAPK1TSHR | |
| SCHEMBL13905068 | 0.82 | BCL2 (0.47) | BCL2SMN1; SMN2KMT2ALMNAHTT | |
| SCHEMBL7770956 | 0.80 | LMNA (0.46) | BCL2SMN1; SMN2KMT2ALMNAHTT | |
| SCHEMBL9035844 | 0.80 | BCL2 (0.46) | BCL2SMN1; SMN2KMT2ALMNAHTT | |
| SCHEMBL7770954 | 0.80 | BCL2 (0.46) | BCL2SMN1; SMN2KMT2ALMNAHTT | |
| SCHEMBL6650513 | 0.80 | BCL2 (0.46) | BCL2SMN1; SMN2KMT2ALMNAHTT | |
| SCHEMBL12164760 | 0.80 | BCL2 (0.46) | BCL2SMN1; SMN2KMT2ALMNAHTT | |
| SCHEMBL8255903 | 0.80 | BCL2 (0.46) | BCL2SMN1; SMN2KMT2ALMNAHTT | |
| Acetic Acid SCHEMBL27734248 | 0.79 | BCL2 (0.56) | BCL2SMN1; SMN2MAPK1L3MBTL1TSHR | |
| SCHEMBL17430387 | 0.79 | ALDH1A1 (0.52) | SMN1; SMN2KMT2ALMNATDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016005474-A1 | SITE SELECTIVE CONJUGATION OF AN OLIGONUCLEOTIDE CONJUGATE OR A SMALL MOLECULE TO A METAL BINDING PROTEIN | AFFYCON APS (DK) | 2016-01-14 | — | — | WO | disclosed |