SCHEMBL17430799

SCHEMBL17430799

CCc1cccc(C[N+]23CC[N+](Cc4cccc(CC)c4)(CC2)CC3)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.49
ACHE P22303 1/20 0.49
TP53 P04637 1/20 0.41
CHRNA7 P36544 4/20 0.39
MGLL Q99685 1/20 0.38
NISCH Q9Y2I1 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2A6 P11509 1/20 0.38
BCL2 P10415 1/20 0.36
RAPGEF4 Q8WZA2 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
NOS3 P29474 1/20 0.35
NOS1 P29475 1/20 0.35
NOS2 P35228 1/20 0.35
IDO1 P14902 1/20 0.35
TRPA1 O75762 1/20 0.34
HIF1A Q16665 1/20 0.34
KIF11 P52732 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL166894 0.79 TP53 (0.61) TP53MGLLNISCHCYP1A2CYP2A6
Ammonia Solution, Strong SCHEMBL28805948 0.77 TP53 (0.58) TP53MGLLNISCHCYP1A2CYP2A6
Benzene SCHEMBL9785236 0.77 TP53 (0.67) TP53MGLLNISCHCYP1A2CYP2A6
SCHEMBL28256639 0.77 TP53 (0.58) TP53MGLLNISCHCYP1A2CYP2A6
Ethylene SCHEMBL27256792 0.74 TP53 (0.55) TP53MGLLNISCHCYP1A2CYP2A6
Hydrogen Peroxide SCHEMBL11520377 0.74 TP53 (0.63) TP53MGLLCYP1A2CYP2A6BCL2
Ethyne SCHEMBL28293458 0.74 TP53 (0.55) TP53MGLLNISCHCYP1A2CYP2A6
Methyl Alcohol SCHEMBL28745884 0.74 TP53 (0.55) TP53MGLLCYP1A2CYP2A6BCL2
SCHEMBL12345521 0.73 TP53 (0.48) TP53MGLLNISCHCYP1A2CYP2A6
SCHEMBL18824415 0.72 NISCH (0.50) BCHEACHETP53MGLLNISCH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9328200-B2 Branched polymeric quaternary ammonium compounds and their uses ULTRASCI DISCOVERY LLP (US) 2016-05-03 US disclosed
US-20160009861-A1 Branched Polymeric Quaternary Ammonium Compounds and Their Uses CHEN HWANG-HSING (US) 2016-01-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160009861-A1 Branched Polymeric Quaternary Ammonium Compounds and Their Uses BCAT2, UACA, BCAT1 BCHE 95/4885ACHE 927/4885TP53 1375/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.