Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 7/20 | 0.33 |
| ▸ | CA2 | P00918 | 7/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
| ▸ | STAT1 | P42224 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL403539 | 0.91 | SIRT5 (0.41) | MEN1KMT2AMAPTKDM4ETDP1 | |
| SCHEMBL19763389 | 0.91 | SIRT5 (0.41) | MEN1KMT2AMAPTKDM4ETDP1 | |
| SCHEMBL403538 | 0.91 | SIRT5 (0.41) | MEN1KMT2AMAPTKDM4ETDP1 | |
| SCHEMBL404498 | 0.91 | METTL3 (0.41) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL404499 | 0.91 | METTL3 (0.41) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL4342987 | 0.89 | MEN1 (0.34) | MEN1KMT2AALDH1A1KDM4ESIRT5 | |
| SCHEMBL4344186 | 0.88 | MEN1 (0.32) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL16596981 | 0.87 | ALDH1A1 (0.38) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL14970638 | 0.87 | ALDH1A1 (0.38) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL407634 | 0.83 | SIRT5 (0.41) | MEN1KMT2AMAPTKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2387998-A1 | Methods for treating degenerative diseases/injuries | Glaxosmithkline LLC (US) | 2011-11-23 | — | — | EP | disclosed |
| US-20110254608-A1 | LEVEL CONTROL CIRCUIT, LEVEL CONTROL METHOD, AND LEVEL CONTROL SYSTEM | FUJITSU LIMTED (JP) | 2011-10-20 | — | — | US | disclosed |