Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | HSD17B3 | P37058 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 3/20 | 0.42 |
| ▸ | THRA | P10827 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19043219 | 0.84 | ALDH1A1 (0.52) | ALDH1A1ATMMEN1KMT2APLK1 | |
| SCHEMBL30089549 | 0.82 | ALDH1A1 (0.64) | ALDH1A1ATMMEN1KMT2APLK1 | |
| SCHEMBL21176949 | 0.81 | ALDH1A1 (0.53) | ALDH1A1ATMMEN1KMT2APLK1 | |
| SCHEMBL11006754 | 0.81 | KMT2A (0.58) | ALDH1A1ATMMEN1KMT2AHPGD | |
| SCHEMBL11041433 | 0.79 | ALDH1A1 (0.55) | ALDH1A1ATMMEN1KMT2APLK1 | |
| SCHEMBL2761141 | 0.79 | NPC1 (0.61) | ALDH1A1NPC1RAB9AL3MBTL1HSD17B3 | |
| SCHEMBL5270771 | 0.79 | HSD17B3 (0.67) | ALDH1A1ATMMEN1KMT2APLK1 | |
| SCHEMBL1833485 | 0.78 | NPC1 (0.62) | ALDH1A1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL1528771 | 0.78 | GSK3B (0.53) | ALDH1A1ATMMEN1KMT2AHPGD | |
| SCHEMBL11738823 | 0.78 | GSK3B (0.53) | ALDH1A1ATMMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9399077-B2 | Metallocene compounds and labeled molecules comprising the same for in vivo imaging | APTENIA S.R.L. (IT) | 2016-07-26 | — | — | US | disclosed |
| US-20160008495-A1 | Metallocene Compounds and Labeled Molecules Comprising the Same for In Vivo Imaging | APTENIA S.R.L. (IT) | 2016-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160008495-A1 | Metallocene Compounds and Labeled Molecules Comprising the Same for In Vivo Imaging | MEN1, MPI, TFRC | ALDH1A1 3718/4885ATM 3569/4885MEN1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.