SCHEMBL1743337

SCHEMBL1743337

NCCCCCSc1ccccn1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 2/20 0.56
ALDH1A1 P00352 3/20 0.51
KMT2A Q03164 4/20 0.47
MAPT P10636 2/20 0.47
EHMT2 Q96KQ7 1/20 0.45
EHMT1 Q9H9B1 1/20 0.45
APOBEC3G Q9HC16 1/20 0.45
NPC1 O15118 4/20 0.44
RAB9A P51151 4/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
MEN1 O00255 3/20 0.41
PKM P14618 2/20 0.41
SMN1; SMN2 Q16637 3/20 0.40
NFKB1 P19838 1/20 0.40
NFKB2 Q00653 1/20 0.40
RELA Q04206 1/20 0.40
HPGD P15428 1/20 0.40
LMNA P02545 1/20 0.40
CYP1A2 P05177 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9081971 0.98 HRH1 (0.53) HRH1ALDH1A1KMT2AMAPTEHMT2
SCHEMBL9865701 0.93 ALDH1A1 (0.54) HRH1ALDH1A1KMT2AMAPTEHMT2
Hydrochloric Acid SCHEMBL8615154 0.91 ALDH1A1 (0.53) HRH1ALDH1A1KMT2AMAPTEHMT2
SCHEMBL317308 0.85 ALDH1A1 (0.58) HRH1ALDH1A1KMT2AMAPTEHMT2
SCHEMBL7045517 0.84 ALDH1A1 (0.53) ALDH1A1KMT2AMAPTEHMT2EHMT1
Hydrochloric Acid SCHEMBL1268501 0.83 ALDH1A1 (0.56) HRH1ALDH1A1KMT2AMAPTEHMT2
Hydrochloric Acid SCHEMBL4286924 0.83 ALDH1A1 (0.56) HRH1ALDH1A1KMT2AMAPTEHMT2
SCHEMBL10974209 0.83 ALDH1A1 (0.56) ALDH1A1KMT2AMAPTEHMT2EHMT1
SCHEMBL22820616 0.83 EHMT2 (0.52) HRH1ALDH1A1KMT2AMAPTEHMT2
SCHEMBL4684785 0.82 ALDH1A1 (0.56) ALDH1A1KMT2AMAPTEHMT2EHMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9518063-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-12-13 US claimed
CN-102341401-B New materials with aza-dibenzothiophene or aza-dibenzofuran core for PHOLEDs UNIVERSAL DISPLAY CORP. (US) 2016-02-10 CN claimed
EP-2387576-B1 NEW MATERIALS WITH AZA-DIBENZOTHIOPHENE OR AZA-DIBENZOFURAN CORE FOR PHOLED UNIVERSAL DISPLAY CORP (US) 2016-01-13 EP claimed
US-20150274749-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-10-01 US claimed
EP-2387576-A2 NEW MATERIALS WITH AZA-DIBENZOTHIOPHENE OR AZA-DIBENZOFURAN CORE FOR PHOLED Universal Display Corporation (US) 2011-11-23 EP claimed
US-20100187984-A1 MATERIALS WITH AZA-DIBENZOTHIOPHENE OR AZA-DIBENZOFURAN CORE FOR PHOLED UNIVERSAL DISPLAY CORPORATION (US) 2010-07-29 US claimed
WO-2010083359-A2 NEW MATERIALS WITH AZA-DIBENZOTHIOPHENE OR AZA-DIBENZOFURAN CORE FOR PHOLED UNIVERSAL DISPLAY CORPORATION (US) 2010-07-22 WO claimed
EP-3689882-A1 NEW MATERIALS WITH AZA-DIBENZOTHIOPHENE OR AZA-DIBENZOFURAN CORE FOR PHOLED Universal Display Corporation (US) 2020-08-05 EP disclosed
EP-3318566-B1 AZADIBENZOFURANS FOR ELECTRONIC APPLICATIONS UDC IRELAND LTD (IE) 2020-06-24 EP disclosed
EP-2703405-B1 NEW MATERIALS WITH AZA-DIBENZOTHIOPHENE OR AZA-DIBENZOFURAN CORE FOR PHOLED UNIVERSAL DISPLAY CORP (US) 2020-04-15 EP disclosed
US-20190131547-A1 AZADIBENZOFURANS FOR ELECTRONIC APPLICATIONS UDC IRELAND LTD (IE) 2019-05-02 US disclosed
US-10249827-B2 Azadibenzofurans for electronic applications UDC IRELAND LIMITED (IE) 2019-04-02 US disclosed
EP-3318566-A1 AZADIBENZOFURANS FOR ELECTRONIC APPLICATIONS UDC Ireland Limited (IE) 2018-05-09 EP disclosed
US-8952363-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2015-02-10 US disclosed
WO-2014044722-A1 AZADIBENZOFURANS FOR ELECTRONIC APPLICATIONS BASF SE (DE) 2014-03-27 WO disclosed
EP-2703405-A2 New materials with aza-dibenzothiophene or aza-dibenzofuran core for pholed Universal Display Corporation (US) 2014-03-05 EP disclosed
US-20130060037-A1 MATERIALS WITH AZA-DIBENZOTHIOPHENE OR AZA-DIBENZOFURAN CORE FOR PHOLED UNIVERSAL DISPLAY CORPORATION (US) 2013-03-07 US disclosed
EP-2387576-A2 NEW MATERIALS WITH AZA-DIBENZOTHIOPHENE OR AZA-DIBENZOFURAN CORE FOR PHOLED Universal Display Corporation (US) 2011-11-23 EP disclosed
US-20100187984-A1 MATERIALS WITH AZA-DIBENZOTHIOPHENE OR AZA-DIBENZOFURAN CORE FOR PHOLED UNIVERSAL DISPLAY CORPORATION (US) 2010-07-29 US disclosed
WO-2010083359-A2 NEW MATERIALS WITH AZA-DIBENZOTHIOPHENE OR AZA-DIBENZOFURAN CORE FOR PHOLED UNIVERSAL DISPLAY CORPORATION (US) 2010-07-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150274749-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES DDT, AZI2, EED HRH1 3798/4885ALDH1A1 399/4885KMT2A 354/4885
US-20190131547-A1 AZADIBENZOFURANS FOR ELECTRONIC APPLICATIONS AZI2, BRPF1, CCNB1 HRH1 1725/4885ALDH1A1 547/4885KMT2A 2395/4885
US-20130060037-A1 MATERIALS WITH AZA-DIBENZOTHIOPHENE OR AZA-DIBENZOFURAN CORE FOR PHOLED DDT, FZD7, BRD7 HRH1 3822/4885ALDH1A1 1449/4885KMT2A 816/4885
US-10249827-B2 Azadibenzofurans for electronic applications AZI2, BRPF1, CCNB1 HRH1 1725/4885ALDH1A1 547/4885KMT2A 2395/4885
US-20100187984-A1 MATERIALS WITH AZA-DIBENZOTHIOPHENE OR AZA-DIBENZOFURAN CORE FOR PHOLED DDT, FZD7, BRD7 HRH1 3822/4885ALDH1A1 1449/4885KMT2A 816/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.