Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 7/20 | 0.70 |
| ▸ | CES2 | O00748 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29035921 | 0.85 | CES1 (0.70) | CES1CES2TSHRALDH1A1DAO | |
| Benzene SCHEMBL27672585 | 0.82 | CES1 (1.00) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL7907262 | 0.82 | CES1 (0.73) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL33083 | 0.82 | CES1 (1.00) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL1799477 | 0.81 | CES1 (0.64) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL27972618 | 0.81 | CES1 (0.64) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL9419966 | 0.81 | CES1 (0.64) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL31083855 | 0.80 | CES1 (0.95) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL29393401 | 0.80 | CES1 (0.95) | CES1CES2TSHRALDH1A1DAO | |
| Fluoride SCHEMBL27824066 | 0.80 | CES1 (0.95) | CES1CES2TSHRALDH1A1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117326923-A | Fluorine-containing dihydronaphthalenone derivative and preparation method and application thereof | 上海应用技术大学 | 2024-01-02 | — | — | CN | claimed |
| CN-118239874-A | Difluoro alkenyl thiocyanate compound and preparation method and application thereof | 上海应用技术大学 | 2024-06-25 | — | — | CN | disclosed |
| CN-117326923-A | Fluorine-containing dihydronaphthalenone derivative and preparation method and application thereof | 上海应用技术大学 | 2024-01-02 | — | — | CN | disclosed |
| CN-113501766-B | Asymmetric synthesis method of multi-functional cyclopentenone derivative containing difluoroalkyl | 重庆大学 | 2023-05-23 | — | — | CN | disclosed |
| CN-115838338-A | Method for preparing amide | 浙江工业大学 | 2023-03-24 | — | — | CN | disclosed |
| US-20160130328-A1 | Pathogen Binding Agents Conjugated to Radioisotopes and Uses in Imaging and Therapeutic Applications | EMORY UNIVERSITY | 2016-05-12 | — | — | US | disclosed |
| EP-2388253-B1 | THIAZOLE DERIVATIVE AND PROCESS FOR PRODUCING SAME | UNIV GIFU (JP) | 2015-02-11 | — | — | EP | disclosed |
| US-8871944-B2 | Thiazole derivative and process for producing same | GIFU UNIVERSITY (JP) | 2014-10-28 | — | — | US | disclosed |
| US-20110319616-A1 | THIAZOLE DERIVATIVE AND PROCESS FOR PRODUCING SAME | GIFU UNIVERSITY (JP) | 2011-12-29 | — | — | US | disclosed |
| EP-2388253-A1 | THIAZOLE DERIVATIVE AND PROCESS FOR PRODUCING SAME | Gifu University (JP) | 2011-11-23 | — | — | EP | disclosed |
| US-20080267882-A1 | Multimeric RGD (arginine-glycine-aspartic acid (Arg-Gly-Asp)) peptide; positron emission tomography; angiogenesis; kits | STANFORD UNIVERSITY (US) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110319616-A1 | THIAZOLE DERIVATIVE AND PROCESS FOR PRODUCING SAME | TST, TALDO1, TBCD | CES1 2453/4885CES2 1257/4885TSHR 164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.