Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 2/20 | 0.69 |
| ▸ | RAB9A | P51151 | 5/20 | 0.69 |
| ▸ | NPC1 | O15118 | 5/20 | 0.69 |
| ▸ | MAPT | P10636 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 7/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | HTR2B | P41595 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27830839 | 0.98 | IMPDH2 (0.68) | IMPDH2RAB9ANPC1MAPTMEN1 | |
| SCHEMBL9637653 | 0.83 | MEN1 (0.77) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL30051982 | 0.83 | MEN1 (0.77) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL9547503 | 0.83 | RAB9A (0.89) | IMPDH2RAB9ANPC1MAPTMEN1 | |
| SCHEMBL11049543 | 0.82 | MAPT (1.00) | IMPDH2RAB9ANPC1MAPTMEN1 | |
| SCHEMBL30697002 | 0.82 | MAPT (1.00) | IMPDH2RAB9ANPC1MAPTMEN1 | |
| SCHEMBL10665495 | 0.82 | RAB9A (0.79) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL20353575 | 0.82 | IMPDH2 (1.00) | IMPDH2RAB9ANPC1MAPTTAAR1 | |
| Bromide SCHEMBL29417998 | 0.82 | MEN1 (0.74) | RAB9ANPC1MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL29388210 | 0.82 | MEN1 (0.74) | RAB9ANPC1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9730945-B2 | Diagnosis of autism spectrum disorders and its treatment with an antagonist or inhibitor of the 5-HT2c receptor signaling pathway | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-08-15 | — | — | US | disclosed |
| US-8940732-B2 | Diagnosis of autism spectrum disorders and its treatment with an antagonist or inhibitor of the 5-HT2c receptor signaling pathway | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-01-27 | — | — | US | disclosed |
| WO-2012149472-A2 | METHODS, COMPOSITIONS, AND KITS FOR TREATING AND PREVENTING NEUROLOGICAL CONDITIONS | IGNITE INSTITUTE FOR INDIVIDUALIZED HEALTH (US) | 2012-11-01 | — | — | WO | disclosed |
| CN-102348798-A | Diagnosis and treatment of autism spectrum disorders | MASSACHUSETTS INST TECHNOLOGY | 2012-02-08 | — | — | CN | disclosed |
| EP-2387611-A1 | DIAGNOSIS AND TREATMENT OF AUTISM SPECTRUM DISORDERS | Massachusetts Institute of Technology (US) | 2011-11-23 | — | — | EP | disclosed |
| US-8040693-B2 | Universal expandable patch panel bracket | PANDUIT CORP. (US) | 2011-10-18 | — | — | US | disclosed |
| US-20100298304-A1 | DIAGNOSIS AND TREATMENT OF AUTISM SPECTRUM DISORDERS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-11-25 | — | — | US | disclosed |
| WO-2010083044-A1 | DIAGNOSIS AND TREATMENT OF AUTISM SPECTRUM DISORDERS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-07-22 | — | — | WO | disclosed |