Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.42 |
| ▸ | POLQ | O75417 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.38 |
| ▸ | MEN1 | O00255 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | IL2 | P60568 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8260166 | 0.85 | ALDH1A1 (0.47) | ADORA3POLQMAPTGAAMAPK1 | |
| SCHEMBL2787427 | 0.80 | STIM1 (0.48) | ADORA3MAPTGAAMAPK1ALDH1A1 | |
| SCHEMBL15395975 | 0.77 | LMNA (0.43) | MAPTGAAALDH1A1KDM4EKMT2A | |
| SCHEMBL17435137 | 0.75 | AGPAT2 (0.41) | MAPTGAAKDM4EKMT2AMEN1 | |
| SCHEMBL17435144 | 0.74 | IL2 (0.38) | IL2 | |
| SCHEMBL17435134 | 0.74 | IL2 (0.40) | MAPTIL2 | |
| SCHEMBL17435143 | 0.73 | IL2 (0.39) | IL2 | |
| SCHEMBL17435124 | 0.73 | IL2 (0.38) | IL2 | |
| SCHEMBL17435138 | 0.73 | IL2 (0.39) | IL2 | |
| SCHEMBL17435133 | 0.73 | IL2 (0.40) | IL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1848435-B1 | COMPOUNDS AGAINST INFLAMMATIONS AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP (US) | 2016-01-20 | — | — | EP | claimed |