SCHEMBL1743543

SCHEMBL1743543

CO[Si](OC)(OC)c1cccc2ccccc12.Cl[Si](Cl)(Cl)Cc1cccc2ccccc12

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.39
CYP2C19 P33261 2/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.38
ATM Q13315 1/20 0.37
NPBWR1 P48145 3/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
MAPK1 P28482 1/20 0.36
CETP P11597 1/20 0.35
AKR1B1 P15121 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29503122 0.82 ALDH1A1 (0.43) CYP1A2CYP2C19CYP2D6TDP1KDM4E
SCHEMBL32679351 0.82 CYP1A2 (0.52) CYP1A2CYP2C19CYP2D6CYP2C9TDP1
SCHEMBL32679352 0.82 CYP1A2 (0.52) CYP1A2CYP2C19CYP2D6CYP2C9TDP1
SCHEMBL105580 0.82 ALDH1A1 (0.43) CYP1A2CYP2C19CYP2D6TDP1KDM4E
SCHEMBL1666987 0.82 CYP1A2 (0.52) CYP1A2CYP2C19CYP2D6CYP2C9TDP1
SCHEMBL2817986 0.74 CYP1A2 (0.48) CYP1A2CYP2C19CYP2D6CYP2C9ATM
SCHEMBL29975538 0.74 CYP1A2 (0.48) CYP1A2CYP2C19CYP2D6CYP2C9ATM
SCHEMBL28453191 0.73 HPGD (0.37) CYP1A2CYP2C19CYP2D6NPBWR1KDM4E
SCHEMBL28172908 0.73 HPGD (0.37) CYP1A2CYP2C19CYP2D6NPBWR1KDM4E
SCHEMBL2546879 0.73 HPRT1 (0.52) CYP1A2ATML3MBTL1TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3743464-A1 ORGANIC-INORGANIC AEROGEL COMPOSITES, METHODS AND USES THEREOF Bronx Creative&Design Centre Pte Ltd (SG) 2020-12-02 EP disclosed
WO-2019147183-A1 ORGANIC-INORGANIC AEROGEL COMPOSITES, METHODS AND USES THEREOF BRONX CREATIVE & DESIGN CENTRE PTE LTD (SG) 2019-08-01 WO disclosed
EP-2387502-A1 METHOD FOR TREATING A HYDROPHILIC SURFACE Sakhrani, Vinay G. (US) 2011-11-23 EP disclosed
US-D647178-S1 Faucet MASCO CORPORATION OF INDIANA (US) 2011-10-18 US disclosed
WO-2010083437-A1 METHOD FOR TREATING A HYDROPHILIC SURFACE SAKHRANI VINAY G (US) 2010-07-22 WO disclosed