SCHEMBL2546879

SCHEMBL2546879

CO[Si](OC)(OC)c1cccc2c1ccc1ccccc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 3/20 0.52
ALDH1A1 P00352 5/20 0.44
HSD17B10 Q99714 5/20 0.44
TDP1 Q9NUW8 2/20 0.44
CYP2A6 P11509 2/20 0.44
TSHR P16473 2/20 0.44
MAPT P10636 2/20 0.41
CYP3A4 P08684 2/20 0.41
MAPK1 P28482 2/20 0.41
LMNA P02545 1/20 0.41
APEX1 P27695 1/20 0.41
PMP22 Q01453 1/20 0.41
PAX8 Q06710 1/20 0.39
CYP1A2 P05177 3/20 0.39
HPGD P15428 3/20 0.39
HIF1A Q16665 2/20 0.39
CYP1B1 Q16678 1/20 0.39
THRB P10828 1/20 0.39
POLB P06746 1/20 0.37
ERBB2 P04626 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL105580 0.88 ALDH1A1 (0.43) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
SCHEMBL29503122 0.88 ALDH1A1 (0.43) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
SCHEMBL15848196 0.84 HPRT1 (0.50) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
SCHEMBL16487390 0.84 HPRT1 (0.50) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
SCHEMBL28959324 0.82 HPRT1 (0.48) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
SCHEMBL1615832 0.81 TRPM4 (0.42) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
SCHEMBL29777494 0.81 HPRT1 (0.47) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
SCHEMBL3479945 0.81 HPRT1 (0.47) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
SCHEMBL2550554 0.81 HPRT1 (0.47) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
SCHEMBL15848295 0.80 HPRT1 (0.45) HPRT1ALDH1A1HSD17B10TDP1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117716295-A Composition for forming silicon-containing resist underlayer film and silicon-containing resist underlayer film 日产化学株式会社 2024-03-15 CN disclosed
EP-3103842-B1 CURABLE SILICONE COMPOSITION, CURED OBJECT THEREOF, AND OPTICAL SEMICONDUCTOR DEVICE DOW TORAY CO LTD (JP) 2023-01-11 EP disclosed
EP-2553145-B1 ETCH RESISTANT ALUMINA BASED COATINGS PIBOND OY (FI) 2022-09-21 EP disclosed
EP-3039079-B1 CURABLE SILICONE COMPOSITION, CURED PRODUCT THEREOF, AND OPTICAL SEMICONDUCTOR DEVICE DDP SPECIALTY ELECTRONIC MAT US 9 LLC (US) 2022-05-18 EP disclosed
CN-109081921-B Silicon-based hard mask 罗门哈斯电子材料有限责任公司 2021-07-06 CN disclosed
CN-108698851-B Composition for forming coating film and method for producing same 日产化学工业株式会社 2020-11-10 CN disclosed
US-10676643-B2 Coating film-forming composition and process for producing the same NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2020-06-09 US disclosed
CN-107076894-B Infrared shielding composition, cured film, and solid-state imaging device JSR株式会社 2020-01-31 CN disclosed
US-20190144707-A1 COATING FILM-FORMING COMPOSITION AND PROCESS FOR PRODUCING THE SAME NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2019-05-16 US disclosed
EP-3438053-A1 FILM FORMING COMPOSITION AND METHOD FOR PRODUCING SAME Nissan Chemical Industries, Ltd. (JP) 2019-02-06 EP disclosed
US-9312196-B2 Curable silicone composition, cured product thereof, and optical semiconductor DOW CORNING TORAY CO., LTD. (JP) 2016-04-12 US disclosed
US-20150252221-A1 Curable Silicone Composition, Cured Product Thereof, And Optical Semiconductor DOW TORAY CO., LTD. (JP) 2015-09-10 US disclosed
EP-2914664-A1 CURABLE SILICONE COMPOSITION, CURED PRODUCT THEREOF, AND OPTICAL SEMICONDUCTOR DEVICE Dow Corning Toray Co., Ltd. (JP) 2015-09-09 EP disclosed
WO-2014069610-A1 CURABLE SILICONE COMPOSITION, CURED PRODUCT THEREOF, AND OPTICAL SEMICONDUCTOR DEVICE DOW CORNING TORAY CO., LTD. (JP) 2014-05-08 WO disclosed
US-20130143408-A1 ETCH RESISTANT ALUMINA BASED COATINGS SILECS OY (FI) 2013-06-06 US disclosed
US-8389649-B2 Siloxane-based resin composition TORAY INDUSTRIES, INC. (JP) 2013-03-05 US disclosed
EP-2553145-A1 ETCH RESISTANT ALUMINA BASED COATINGS Silecs OY (FI) 2013-02-06 EP disclosed
WO-2011121166-A1 ETCH RESISTANT ALUMINA BASED COATINGS SILECS OY (FI) 2011-10-06 WO disclosed
US-20100316953-A1 SILOXANE-BASED RESIN COMPOSITION TORAY INDUSTRIES, INC. (JP) 2010-12-16 US disclosed
EP-2239301-A1 SILOXANE RESIN COMPOSITIONS Toray Industries, Inc. (JP) 2010-10-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100316953-A1 SILOXANE-BASED RESIN COMPOSITION ICAM1, ESD, CAD HPRT1 2773/4885ALDH1A1 599/4885HSD17B10 1203/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.