SCHEMBL105580

SCHEMBL105580

CO[Si](OC)(OC)c1cccc2ccccc12

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.43
CYP2A6 P11509 5/20 0.43
POLB P06746 1/20 0.42
KDM4E B2RXH2 1/20 0.41
MAPK1 P28482 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
MAPT P10636 1/20 0.41
TSHR P16473 3/20 0.40
HSD17B10 Q99714 2/20 0.40
TDP1 Q9NUW8 1/20 0.40
CYP1A2 P05177 5/20 0.38
CYP3A4 P08684 1/20 0.38
HPGD P15428 1/20 0.38
KEAP1 Q14145 1/20 0.38
HPRT1 P00492 1/20 0.37
RAB9A P51151 1/20 0.37
CYP2C19 P33261 2/20 0.37
CYP2D6 P10635 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29503122 1.00 ALDH1A1 (0.43) ALDH1A1CYP2A6POLBKDM4EMAPK1
SCHEMBL2546879 0.88 HPRT1 (0.52) ALDH1A1CYP2A6POLBMAPK1MAPT
SCHEMBL28172908 0.85 HPGD (0.37) ALDH1A1CYP2A6POLBKDM4EMAPK1
SCHEMBL28670782 0.85 MAPT (0.42) ALDH1A1CYP2A6POLBKDM4EMAPK1
SCHEMBL28453191 0.85 HPGD (0.37) ALDH1A1CYP2A6POLBKDM4EMAPK1
SCHEMBL1974165 0.84 ALDH1A1 (0.34) ALDH1A1CYP2A6POLBKDM4EMAPK1
SCHEMBL6702615 0.84 HTR1B (0.38) ALDH1A1CYP2A6POLBMAPTTSHR
SCHEMBL15067729 0.83 ALDH1A1 (0.43) ALDH1A1CYP2A6POLBKDM4EMAPK1
SCHEMBL5043689 0.83 CYP2A6 (0.43) ALDH1A1CYP2A6POLBKDM4EMAPK1
SCHEMBL29404894 0.83 CYP2A6 (0.43) ALDH1A1CYP2A6POLBKDM4EMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1228 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12516263-B2 Compositions for reducing friction or stiction of a surface, methods and articles comprising the same ACTNANO, INC. (US) 2026-01-06 US claimed
US-20260000623-A1 DRUG DELIVERY BY PORE-MODIFIED MESOPOROUS SILICA NANOPARTICLES CHAN, Hardy Wai Hong (TW) 2026-01-01 US claimed
EP-4665801-A1 COMPOSITIONS FOR REDUCING FRICTION OR STICTION OF A SURFACE, METHODS AND ARTICLES COMPRISING THE SAME Actnano, Inc. (US) 2025-12-24 EP claimed
CN-120041122-A Epoxy resin underfill adhesive and preparation method thereof 深圳先进电子材料国际创新研究院 2025-05-27 CN claimed
CN-119633738-A Adsorbent and preparation method and application thereof 河北鑫鹏新材料科技有限公司 2025-03-18 CN claimed
CN-118978701-A Low-viscosity alkoxy-rich hyperbranched organic silicon resin and preparation method and application thereof 南京大学 2024-11-19 CN claimed
US-20240352315-A1 METHODS AND COMPOSITIONS FOR ENHANCED DISPERSION OF PHOSPHOR IN A POLYMERIC MATRIX BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2024-10-24 US claimed
US-20240279564-A1 COMPOSITIONS FOR REDUCING FRICTION OR STICTION OF A SURFACE, METHODS AND ARTICLES COMPRISING THE SAME ACTNANO, INC. 2024-08-22 US claimed
WO-2024173535-A1 COMPOSITIONS FOR REDUCING FRICTION OR STICTION OF A SURFACE, METHODS AND ARTICLES COMPRISING THE SAME ACTNANO, INC. (US) 2024-08-22 WO claimed
CN-118109052-A Damping silicon rubber and preparation method and application thereof 新安天玉有机硅有限公司 2024-05-31 CN claimed
US-8993214-B2 Positive photosensitive siloxane composition AZ ELECTRONIC MATERIALS USA CORP. (US) 2015-03-31 US claimed
EP-2628745-B1 Silicon-containing surface modifier, resist lower layer film-forming composition containing the same, and patterning process SHINETSU CHEMICAL CO (JP) 2015-03-25 EP claimed
US-20140335452-A1 POSITIVE PHOTOSENSITIVE SILOXANE COMPOSITION AZ ELECTRONIC MATERIALS USA CORP. (US) 2014-11-13 US claimed
CN-103801394-A Organic modified hydrophobic nano solid acid material and preparation thereof DALIAN CHEMICAL PHYSICS INST 2014-05-21 CN claimed
CN-103803556-A Organic modified hydrophobic nano silica hollow ball and preparation method thereof DALIAN CHEMICAL PHYSICS INST 2014-05-21 CN claimed
EP-2567940-A1 Method for preparing clays having novel physical-chemical properties Ecole De Biologie Industrielle (EBI) (FR) 2013-03-13 EP claimed
WO-2009120410-A2 HIGH REFRACTIVE INDEX SOL-GEL COMPOSITION AND METHOD OF MAKING PHOTO-PATTERNED STRUCTURES ON A SUBSTRATE NITTO DENKO CORPORATION (JP) 2009-10-01 WO claimed
US-20090246716-A1 HIGH REFRACTIVE INDEX SOL-GEL COMPOSITION AND METHOD OF MAKING PHOTO-PATTERNED STRUCTURES ON A SUBSTRATE NITTO DENKO CORPORATION (JP) 2009-10-01 US claimed
US-20090075002-A1 Block copolymer nanostructure formed on surface pattern with shape different from nanostructure of the block copolymer and method for preparation thereof KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2009-03-19 US claimed
WO-2008147044-A1 NANO STRUCTURE OF BLOCK COPOLYMER AND METHOD FOR PREPARING THE SAME KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2008-12-04 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090246716-A1 HIGH REFRACTIVE INDEX SOL-GEL COMPOSITION AND METHOD OF MAKING PHOTO-PATTERNED STRUCTURES ON A SUBSTRATE SOS1, SOS2, MMS19 ALDH1A1 2390/4885CYP2A6 3977/4885POLB 1982/4885
US-20260000623-A1 DRUG DELIVERY BY PORE-MODIFIED MESOPOROUS SILICA NANOPARTICLES AQP4, ABCB1, SRMS ALDH1A1 2548/4885CYP2A6 606/4885POLB 3373/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.