Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 6/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.56 |
| ▸ | AURKA | O14965 | 1/20 | 0.56 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.56 |
| ▸ | JAK2 | O60674 | 1/20 | 0.56 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17438132 | 1.00 | CYP1A2 (0.73) | CYP1A2CYP2C19KMT2AALDH1A1LMNA | |
| SCHEMBL17452448 | 0.84 | CYP1A2 (1.00) | CYP1A2CYP2C19KMT2AALDH1A1LMNA | |
| SCHEMBL685119 | 0.82 | NPC1 (0.77) | CYP1A2CYP2C19KMT2AALDH1A1RAB9A | |
| SCHEMBL6570259 | 0.82 | NPC1 (0.77) | CYP1A2CYP2C19KMT2AALDH1A1RAB9A | |
| SCHEMBL6570260 | 0.82 | NPC1 (0.77) | CYP1A2CYP2C19KMT2AALDH1A1RAB9A | |
| SCHEMBL8265458 | 0.81 | ALDH1A1 (0.56) | CYP1A2CYP2C19KMT2AALDH1A1LMNA | |
| SCHEMBL684903 | 0.79 | KMT2A (0.78) | CYP1A2CYP2C19KMT2AALDH1A1LMNA | |
| SCHEMBL685177 | 0.78 | PIK3CG (0.67) | KMT2AALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL684567 | 0.78 | MEN1 (0.70) | KMT2ALMNARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL17452446 | 0.77 | LMNA (1.00) | CYP1A2CYP2C19KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10730848-B2 | Protective molecules against anthrax toxin | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-08-04 | — | — | US | disclosed |
| US-20160016930-A1 | PROTECTIVE MOLECULES AGAINST ANTHRAX TOXIN | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160016930-A1 | PROTECTIVE MOLECULES AGAINST ANTHRAX TOXIN | ANTXR2, TSG101, ANXA1 | CYP1A2 3491/4885CYP2C19 4603/4885KMT2A 4471/4885 |
| US-10730848-B2 | Protective molecules against anthrax toxin | ANTXR2, TSG101, ANXA1 | CYP1A2 3491/4885CYP2C19 4603/4885KMT2A 4471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.