Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIG1 | P18858 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TLR4 | O00206 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SETDB1 | Q15047 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7723507 | 0.85 | LIG1 (0.58) | LIG1HPGDTSHRMAPK1HSD17B10 | |
| Hydrochloric Acid SCHEMBL7722654 | 0.84 | LIG1 (0.56) | LIG1HPGDTSHRMAPK1HSD17B10 | |
| SCHEMBL9774243 | 0.79 | LIG1 (0.55) | LIG1HPGDTSHRMAPK1HSD17B10 | |
| SCHEMBL1628363 | 0.79 | TSHR (0.50) | LIG1HPGDTSHRMAPK1HSD17B10 | |
| SCHEMBL13400836 | 0.78 | LIG1 (0.54) | LIG1HPGDTSHRMAPK1HSD17B10 | |
| SCHEMBL3944765 | 0.78 | LIG1 (0.54) | LIG1HPGDTSHRMAPK1HSD17B10 | |
| SCHEMBL3937140 | 0.76 | LIG1 (0.55) | LIG1HPGDTSHRKDM4EPOLB | |
| SCHEMBL7072808 | 0.75 | HPGD (0.47) | LIG1HPGDTSHRMAPK1HSD17B10 | |
| SCHEMBL2470333 | 0.75 | LIG1 (0.54) | LIG1HPGDTSHRMAPK1HSD17B10 | |
| SCHEMBL28071261 | 0.74 | TSHR (0.46) | LIG1HPGDTSHRMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9981070-B2 | Coating composition and medical device | TERUMO KABUSHIKI KAISHA (JP) | 2018-05-29 | — | — | US | disclosed |
| US-20160015864-A1 | COATING COMPOSITION AND MEDICAL DEVICE | TERUMO KABUSHIKI KAISHA (JP) | 2016-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160015864-A1 | COATING COMPOSITION AND MEDICAL DEVICE | CUTA, MLEC, PHOSPHO1 | LIG1 3238/4885HPGD 3172/4885TSHR 4631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.