Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.61 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.57 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.57 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5698418 | 1.00 | PTGS2 (0.64) | PTGS2PTGS1AKR1C2AKR1C1AKR1C3 | |
| SCHEMBL16052791 | 1.00 | PTGS2 (0.64) | PTGS2PTGS1AKR1C2AKR1C1AKR1C3 | |
| SCHEMBL9720721 | 0.89 | MAOB (0.55) | PTGS2PTGS1AKR1C2AKR1C1AKR1C3 | |
| SCHEMBL9720723 | 0.89 | MAOB (0.55) | PTGS2PTGS1AKR1C2AKR1C1AKR1C3 | |
| SCHEMBL444872 | 0.87 | PTGS2 (0.69) | PTGS2PTGS1 | |
| Water SCHEMBL27918427 | 0.84 | PTGS2 (0.67) | PTGS2PTGS1 | |
| SCHEMBL7492252 | 0.82 | NFE2L2 (0.62) | PTGS2PTGS1AKR1C3NFE2L2 | |
| SCHEMBL9720714 | 0.81 | MAOB (0.49) | PTGS2PTGS1AKR1C2AKR1C1AKR1C3 | |
| SCHEMBL27722400 | 0.81 | PTGS2 (0.59) | PTGS2AKR1C2AKR1C1AKR1C3 | |
| SCHEMBL6470141 | 0.80 | PTGS2 (0.74) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160016860-A1 | METHODS FOR PHOSPHINE OXIDE REDUCTION IN CATALYTIC WITTIG REACTIONS | DUBLIN CITY UNIVERSITY (IE) | 2016-01-21 | — | — | US | disclosed |
| US-20160016860-A1 | METHODS FOR PHOSPHINE OXIDE REDUCTION IN CATALYTIC WITTIG REACTIONS | DUBLIN CITY UNIVERSITY (IE) | 2016-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160016860-A1 | METHODS FOR PHOSPHINE OXIDE REDUCTION IN CATALYTIC WITTIG REACTIONS | DCXR, TECR, PWWP2B | PTGS2 585/4885PTGS1 1284/4885AKR1C2 387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.